Chemistry Associate Scientist in Kalodimos Lab

St. Jude Children's Research Hospital•Memphis, TN

1d•Onsite

About The Position

We are seeking an Associate Scientist to join our Blue Sky Protein Kinases team in the Department of Structural Biology at St. Jude Children's Research Hospital. At St. Jude Children’s Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That’s why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children.

Requirements

Bachelor’s degree in a relevant scientific area.
7 + years of research experience is required with a Bachelor's degree.
5 + years of research experience is required with a Master’s degree.
2 + years of research experience is required with a PhD.

Nice To Haves

Extensive hands-on experience in multi-step (≥10 steps) gram-scale synthesis of complex compounds; experience with stable isotope–labeled compounds is highly desirable.
Strong expertise in amino acid purification and analytical methods.
Solid understanding of protein NMR applications utilizing stable isotopes.
Familiarity with cell-based (e.g., bacterial or insect) and cell-free protein synthesis systems for stable isotope–labeled protein production.
Demonstrated ability to manage multiple research projects simultaneously, maintain thorough daily documentation of experimental work, and consistently meet deadlines.

Responsibilities

Design, synthesize, and optimize stable isotope–labeled amino acids and related derivatives that serve as precursors for isotope-labeled proteins used in protein NMR studies.
Perform separation, purification, and analytical characterization of amino acids.
Operate and perform routine maintenance of synthetic chemistry equipment, and manage personal synthesis schedules to ensure timely project completion.
Deliver synthesized reagents to the protein preparation team in a timely manner to meet project deadlines.