Associate Scientist - Analytical and Biological Mass Spectrometry (ABMS)

Regeneron PharmaceuticalsTarrytown, GA
$70,300 - $110,100Onsite

About The Position

Regeneron Pharmaceutical's Analytical and Biological Mass Spectrometry Group (ABMS), located in Tarrytown, NY is seeking a highly motivated Associate Scientist. In this role, you will work in an innovative mass spectrometry lab and execute LC-MS methods for characterizing biotherapeutic products to support all stages of drug development, from early-stage candidate selections to late-stage regulatory submissions. You will perform routine technical tasks to support a diverse R&D pipeline.

Requirements

  • Bachelor’s or Master’s degree in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a closely related field.
  • Familiarity with advanced mass spectrometers (Q Exactive Plus, Q Exactive UHMR, Q-TOF, etc.), liquid chromatography, liquid-handling systems and data processing software (Skyline, Protein Metrics, etc.) is desired.
  • Willingness to learn is valued.

Nice To Haves

  • Exposure to automated liquid-handling systems (e.g., Bravo, KingFisher) is a plus.

Responsibilities

  • Execute established protocols and clearly communicate analytical characterization of biotherapeutics, including monoclonal and bispecific antibodies, Fc-fusion proteins, and other modalities (adeno-associated virus, siRNA, etc.) to support drug development.
  • Execute characterization activities, with an emphasis on intact-mass LC-MS technique to elucidate critical quality attributes such as charge variants, size variants, and post-translational modifications.
  • Provide analytical support for cross-functional teams, including formulation development, upstream/downstream process development, and manufacturing to solve drug development challenges.
  • Independently conduct sample preparation and LC-MS analyses in compliance with SOPs and document experimental procedures and results in electronic laboratory notebook (ELN).
  • Use strong organization and communication to plan and prioritize work, manage and visualize data, and deliver clear, timely updates.

Benefits

  • health and wellness programs (including medical, dental, vision, life, and disability insurance)
  • fitness centers
  • 401(k) company match
  • family support benefits
  • equity awards
  • annual bonuses
  • paid time off
  • paid leaves (e.g., military and parental leave)
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