Associate Principal Scientist, Health Economic and Decision Sciences

Merck•Boston, MA
•$156,900 - $247,000•Hybrid

About The Position

The Associate Principal Scientist joins the Oncology health economic modeling team within the Health Economic and Decision Sciences (HEDS) group, part of the Biostatistics and Research Decision Sciences organization. Under the direction of an HEDS Senior Director, this role provides strategic development and use of predictive and economic models to improve understanding of disease and quantify and communicate the value of oncology products to patients, providers, and payers. The preferred location is West Point, Pennsylvania; Rahway, New Jersey, Boston, the UK, and Switzerland may also be considered. Hybrid and flexible work arrangements are possible under local policies. The role applies discovery, real-world evidence, clinical trial, published, and publicly available data and tools to develop integrated economic, disease, and predictive models throughout drug and vaccine development, from Phase I through loss of data exclusivity. It develops and maintains global health economic models and tools, supports adaptations by country and regional teams, and communicates findings to internal and external stakeholders. The position collaborates with cross-functional colleagues, external vendors, clinical and economic thought leaders, payer and HTA experts, and alliance partners. It also advances modeling methods and analytics, shares best practices across the enterprise, and disseminates findings through congress presentations and scientific publications.

Requirements

  • Relevant work experience in health economics and outcomes research beyond a PhD or Master’s degree.
  • Knowledge and experience in economic evaluation of oncology drugs and interventions.
  • Expertise and substantial hands-on experience conceptualizing, designing, developing, and disseminating health economic modeling approaches for internal and external decisions.
  • Track record of submissions to Health Technology Assessment bodies and research publications at conferences and in peer-reviewed journals.
  • Strong interpersonal, organizational, and communication skills, including ability to interact with people from varied disciplines.
  • Understanding of the market access environment and challenges in the United States and key international markets.
  • Required skills include data management, economic modeling, health economics, health economics evaluation, health technology assessment, oncology, researching, stakeholder relationship management, and strategic planning.

Nice To Haves

  • PhD in Health Economics, Biostatistics, Health Services Research, Actuarial Sciences, Operations Research, or a closely related quantitative field; a Master’s degree in one of these fields is also accepted.

Responsibilities

  • Serve as the BARDS HEDS lead for one or more Value and Implementation teams, developing health economic, disease, and predictive models to generate product business insights.
  • Use discovery, real-world evidence, clinical trial, published, and publicly available data and tools to develop economic and integrated models that address key questions throughout drug and vaccine development, from Phase I through loss of data exclusivity.
  • Advance integrated quantitative approaches focused on economic, disease, and predictive modeling and simulation, working with internal groups and external organizations.
  • Develop and maintain global health economic models and tools, in-house or with external vendors, to provide business insights and demonstrate the value of company products.
  • Support and train users of HEDS models and tools, including country and regional teams adapting models and communicating with external stakeholders.
  • Present health economic data at congresses and publish findings in scientific journals.
  • Collaborate with external clinical and economic thought leaders, payer and HTA experts, alliance partners, and internal cross-functional teams to ensure effective use of methodologies, models, and advanced analytics.
  • Monitor external data, modeling methodologies, and IT tools, and collaborate with internal stakeholders to enhance health economic modeling, simulation, and data visualization capabilities.
  • Share work products and relevant best practices across the company.

Benefits

  • Medical, dental, and vision healthcare and other insurance benefits for employees and family.
  • Retirement benefits, including 401(k).
  • Paid holidays, vacation, compassionate days, and sick days.
  • Eligible for an annual bonus and long-term incentive, if applicable.
  • Domestic relocation assistance is indicated.
© 2026 Teal Labs, Inc
Privacy PolicyTerms of Service