Associate Director, Site Supply Chain

AstraZeneca • Los Angeles, CA

1d • Hybrid

About The Position

Join AstraZeneca’s Cell Therapy Operations as the Associate Director, Site Supply Chain, leading end-to-end planning and site operations across our Tarzana and Santa Monica, CA manufacturing facilities. You will set and execute the site supply chain strategy to ensure reliable, efficient production and uninterrupted supply of cell therapy products for patients in need. Partnering closely with Manufacturing, Quality, Operations and Global Supply Chain you will drive the S&OE cadence, optimize capacity and inventory, enable new product introductions, and embed resilient processes and digital tools across the network. If you bring deep expertise in supply chain and capacity planning within cell therapy or advanced therapies, this is an opportunity to shape a rapidly scaling platform with meaningful patient impact.

Requirements

• Bachelor’s degree with 10+ years’ experience, or Master’s degree with 8+ years’ experience, in supply chain, operations, or related disciplines.
• Proven track record developing and executing supply chain strategies that improve capacity, inventory levels, production efficiency, service levels, and overall reliability
• Strong knowledge of autologous cell therapy supply chains, including Make-to-Order and Make-to-Stock models, vein-to-vein considerations, and cell therapy capacity planning.
• Advanced analytical capability with the ability to convert data and scenarios into clear recommendations and plans.
• Demonstrated people leadership and cross-functional influence in GMP manufacturing environments.
• Proficiency with ERP and advanced planning systems, demand planning and slot management tools, and inventory optimization solutions.

Nice To Haves

• APICS/ASCM or equivalent certification preferred.
• Degree in Supply Chain Management, Operations Management, Engineering, Sciences, Business Administration, or related field; advanced degree preferred.
• 10+ years across supply chain planning, demand forecasting, inventory management, production planning—ideally in pharma/biotech—with specific experience in cell therapy or advanced therapies.
• Experience implementing digital planning capabilities, network modeling, or scenario planning in highly regulated, high-mix/low-volume operations.

Responsibilities

• Lead the integrated site planning process for Tarzana and Santa Monica to support clinical and commercial manufacturing, including demand review, capacity evaluation, production scheduling, site slot management, and finite scheduling to optimize resources, cycle time, and throughput while maintaining compliance and quality.
• Ensure on-time availability and deployment of material through planning, scheduling and replenishment strategies, and by taking appropriate actions to prevent supply disruptions.
• Responsible for maximizing inventory turns, while minimizing inventory valuation and scrap.
• Build and maintain robust short-, mid-, and long-range capacity scenarios in partnership with Site Operations ; balance labor, cleanroom suites, materials, and critical path steps to maximize utilization and agility.
• Own supply chain inputs to technical changes, process improvements, and new product introductions; conduct change assessments, de-risk launches, and ensure supply continuity through scale-up and tech transfer.
• Accountable for setting up and leading a robust monthly review process (S&OE) that validates the supply plan for 0-36m horizon.
• Improve service, inventory, and cost through standard work, process excellence, and digital enablement; implement planning governance, slotting rules, and exception management to strengthen S&OE and response to variability.
• Build tools for S&OE performance and KPI management to enable continuous improvement of site operations and execution.
• Lead and coach a high-performing team; align stakeholders across Manufacturing, Quality, MS&T, and Global Supply Chain; communicate clear priorities, risks, and trade-offs to senior leadership.
• Drive maximum utilization of enterprise software (ERP), demand planning, slotting, and inventory optimization tools; translate complex data into actionable recommendations that elevate site operations.

Benefits

• short-term incentive bonus opportunity
• equity-based long-term incentive program
• retirement contribution
• commission payment eligibility
• qualified retirement program [401(k) plan]
• paid vacation and holidays
• paid leaves
• health benefits including medical, prescription drug, dental, and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Manager
• Number of Employees: 5,001-10,000 employees