Associate Director, Operations- Center for Therapeutic Genectics

Broad Institute•Cambridge, MA

2d•$131,000 - $183,000•Hybrid

About The Position

The Center for Therapeutic Genetics (CTG), a nonprofit collaboration among the Broad Institute, Boston Children's Hospital, and The Jackson Laboratory, develops genetic medicines for rare and ultra-rare diseases. Its platform approach builds shared design tools, disease models, manufacturing processes, safety data, and clinical protocols to help make treatments faster, safer, less costly, and more accessible. CTG is seeking an Associate Director of Operations to build and lead the center’s operational, financial, and governance infrastructure. Reporting to the CTG Director and working with Broad Institute administration, this role connects strategy to execution across CTG’s program teams and institutional partners. The Associate Director owns the CTG operations budget and partnership infrastructure, sets operational goals, and uses judgment and data to address complex problems. The position requires sufficient understanding of nonclinical and clinical translational work to support CTG’s mission, along with strong business acumen; bench science expertise is not required.

Requirements

Bachelor’s degree with 10 or more years of related experience, a master’s degree with 8 or more years, or a PhD with 5 or more years in project management, alliance management, strategic consulting, or a related field; equivalent experience is considered.
At least 5 years of management experience, including leading teams, programs, or cross-functional efforts.
Advanced understanding of how teams contribute to organizational objectives and working understanding of how a large research institution operates.
Proven ability to manage complex projects, timelines, and multimillion-dollar budgets with accountability for results.
Ability to analyze complex or ambiguous situations, use data to guide decisions, and create practical solutions to unusual problems.
Intellectual agility to understand and communicate complex scientific ideas to varied audiences.
Strategic and tactical capability, balancing big-picture thinking with attention to execution detail.
Strong interpersonal judgment and analytical rigor; ability to build trust and consensus among diverse stakeholders, including senior leaders.
Initiative, problem-solving ability, and willingness to take a hands-on approach.
Exceptional written and verbal communication skills, including the ability to turn complex ideas into clear, actionable materials.

Nice To Haves

Background in science, medicine, or a related field.
Experience with board-level communications.

Responsibilities

Lead CTG’s operational framework, including governance, finance, communications, and logistics, and ensure timely execution across Preclinical, Manufacturing, and Clinical programs and supporting teams.
Help establish CTG’s strategic direction and priorities, translating them into operating plans, timelines, and performance indicators.
Recommend and implement policies, processes, and tools as CTG grows, and select methods and criteria for measuring results.
Lead cross-cutting initiatives spanning multiple teams and institutions.
Oversee and guide experienced staff and project managers, delegate work, and build the capabilities of direct reports and colleagues.
Design, manage, and forecast the CTG operations budget, including internal staff and seconded institutional staff, and contribute to the overall CTG budget.
Take accountability for budget decisions and reporting to fiscal sponsors and partner institutions.
Work with scientific project managers to track program pipelines, milestones, budgets, and timelines, and raise risks to leadership early.
Coordinate logistics, materials, and follow-up for the CTG Oversight Committee, Leadership Teams, and Scientific Advisory Board; document decisions and communicate them to program teams.
Partner with program leads to schedule, resource, and escalate program governance gates, such as go/no-go reviews, to the Governance Committee.
Maintain compliance with partner institutions’ agreed transactional workflows.
Serve as the primary operational partner to founding partners and external collaborators; maintain and refine tri-institutional governance models and attend operational and administrative working group meetings.
Draft and advance memorandums of understanding and related agreements.
Identify, engage, and onboard new partners and resources.
Work with senior leaders on matters affecting multiple teams, influencing decisions and building acceptance in sensitive situations while maintaining relationships.
Prepare and deliver executive- and board-level communications on progress, risks, and milestones; develop and maintain business plans, executive summaries, and presentation decks.
Capture and synthesize partner meeting discussions and drive action items to completion.
Support coordination with the Patient & Community Engagement Council and patient advocacy representatives on the Board.
Serve as interim point of contact for cross-program data and reporting needs until a Head of Data is hired.
Work across Broad Administration to advance CTG goals.