Assistant Research Professor

University of Colorado•Aurora, CO

1d•Onsite

About The Position

The Section of Pediatric Critical Care Medicine at the University of Colorado Denver/Children's Hospital Colorado seeks an Assistant Research Professor responsible for projects investigating the role of redox signaling and inflammation in pulmonary vascular disease. Duties will include research and teaching associated with the laboratory research team. This position will be based at Children's Hospital Colorado in Aurora, CO.

Requirements

PhD with focus on Electron Paramagnetic Resonance Imaging.
Three years' post-graduate research experience
Research expertise in pulmonary and vascular diseases
Publication in area of redox biology and medicine
Research experience investigating inflammation, fibrosis, and tissue redox regulation.
Must successfully pass a drug test through Children’s Hospital Colorado
Must be willing and able to pass a national criminal background check

Nice To Haves

Five years' post-graduate research experience
Strong organizational, record-keeping and interpersonal skills
Skills in molecular, cell, tissue and animal methodologies
Ability to acquire new skills to advance research studies
Ability to communicate effectively
Ability to handle stressful situations with professional composure
Knowledge and skill in customer service delivery
Ability to work well independently
Well-organized and efficient in their work

Responsibilities

Develop new methodologies and perform experiments using Electron Paramagnetic Resonance spectroscopy (EPR) in biomedical research
Prepare samples for EPR experiments using: Circulating monocytes and neutrophils, blood, alveolar fluid, or tissue samples from human clinical studies; Cell culture models; Tissue, isolated primary cells and fluids from animal models of organ injury; Live rodents injected with EPR spin probes/traps
Optimize and perform EPR experiments at room temperature and under liquid nitrogen
Develop protocols for measurement of circulating reactive oxygen species in live mice
Develop and optimize protocols to measure superoxide, nitric oxide, hydrogen peroxide, peroxynitrite, hydroxyl radical, oxidized lipids, oxidized glutathione testing various spin probes or traps
Perform EPR experiments and optimize protocols for differentiation of intracellular, extracellular and mitochondrial superoxide
Develop protocols to measure ROS in cells and rodents under hypoxic conditions
Analyze data and prepare graphs for presentations, manuscripts and grants
Initiate protocols for future development of in vivo EPR program
Training and mentoring graduate students and/or laboratory