Assistant Professor of Medicine

Penn State University • Tallahassee, FL

21h

About The Position

Penn State College of Medicine (PSCOM) is seeking a highly skilled scientist to serve as Director of the Human iPSC & CRISPR Editing Core, a new shared research resource supporting translational and precision medicine research across the COM and Penn State Health (PSH). This position is a dual-role appointment, with 50% effort dedicated to directing the iPSC & CRISPR Editing Core and 50% effort dedicated to research laboratory management within the Department of Medicine (DOM). This role provides an opportunity to build and lead a core facility while maintaining close engagement in active translational research programs.

Requirements

• PhD or equivalent doctoral degree in a relevant biomedical discipline.
• Demonstrated expertise in: Human iPSC generation, maintenance, and differentiation CRISPR/Cas9 genome editing technologies
• Experience managing complex laboratory operations.
• Strong organizational, communication, and leadership skills.
• Ability to work collaboratively in a multidisciplinary academic research environment.

Nice To Haves

• Prior experience leading or contributing to a core facility or shared research resource.
• Expertise in iPSC-derived cardiomyocytes and cardiovascular disease modeling.
• Experience supporting NIH- or VA-funded research programs.
• Familiarity with core facility cost-recovery models.

Responsibilities

• Establish, lead, and operate the Human iPSC & CRISPR Editing Core.
• Oversee generation, propagation, differentiation, and characterization of human iPSCs, including iPSC-derived cardiomyocytes.
• Develop and implement CRISPR/Cas9-based genome editing approaches (knock-in, knock-out, variant modeling).
• Build and manage scalable and high-throughput iPSC-based experimental platforms.
• Provide scientific consultation to investigators on experimental design and feasibility.
• Collaborate with faculty across PSCOM, PSH, and the Department of Molecular and Precision Medicine, including alignment with organoid and precision medicine initiatives.
• Develop and maintain SOPs, quality control standards, and reproducibility practices.
• Oversee core operations, including scheduling, training, and cost-recovery activities.
• Contribute technical expertise to grant applications and progress reports.
• Ensure compliance with institutional biosafety, regulatory, and research policies.
• Serve as senior laboratory manager for a translational cardiovascular research laboratory.
• Oversee daily laboratory operations, including personnel supervision, purchasing, budgeting, and compliance.
• Support and execute experimental workflows involving human iPSC-derived models, genome editing, and functional assays.
• Train and mentor laboratory staff and trainees in advanced cell biology and genome editing techniques.
• Ensure continuity, efficiency, and rigor in laboratory operations and research activities.

Benefits

• Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional wellbeing.
• In addition to comprehensive medical, dental, and vision coverage, employees enjoy robust retirement plans.
• One of the standout benefits is the generous 75% tuition discount, available to employees as well as eligible spouses and children.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees