Metaphore: Antibody Discovery and Molecular Biology Co-Op
About The Position
We are seeking a highly motivated Co-op to support early-stage discovery efforts within our Peripheral Artery Disease (PAD) program, a newly initiated therapeutic discovery program focused on achieving proof-of-concept (POC) by the end of the year. This position will provide hands-on experimental support for routine but mission-critical discovery and molecular biology activities that enable efficient advancement of the program. The role offers meaningful exposure to foundational discovery workflows within a fast-paced, research-focused environment, with opportunities to contribute across additional programs as bandwidth allows. This position is a unique joint effort between the Discovery and Molecular Biology teams, with opportunities to support cloning projects focused on antibody expression, contribute to high-throughput cloning pipelines, and gain exposure to laboratory automation.
Requirements
- Current Northeastern University Co-Op student status.
- A collaborative and adaptable mindset with a positive attitude and a strong willingness to learn new skills.
- Basic molecular biology and protein biochemistry skills.
- Familiarity with standard wet-lab techniques.
- Ability to follow established protocols accurately and reproducibly.
- Strong organizational skills and attention to detail.
- Willingness to work across multiple projects and teams in a dynamic environment.
- Comfort contributing in a fast-paced, resource-conscious discovery setting.
Nice To Haves
- Prior laboratory experience in an academic or industry setting.
- Hands-on experience with phage display, ELISAs, or related assay formats (e.g. yeast or mammalian display).
- Experience with cloning and routine molecular biology techniques such as Gibson or Golden Gate Assembly.
- Basic understanding of protein or antibody biochemistry.
- Experience maintaining clear and accurate experimental records.
Responsibilities
- Executing routine, mission-critical discovery and molecular biology experiments that support target validation, hit identification, and early characterization within the PAD program.
- Hands-on laboratory work using established protocols.
- Contributing to molecular biology techniques supporting library preparation, cloning, and hit screening.
- Supporting antibody selection methodologies, including phage display–based biopanning on PAD-relevant targets.
- Performing ELISA-based screening and other binding and characterization assays.
- Assisting with cloning projects supporting antibody expression and high-throughput cloning pipelines.
- Contributing to laboratory automation workflows, as applicable.
- Executing additional foundational assays required to advance early discovery milestones efficiently.
- Generating high-quality experimental data that supports timely decision-making and progress toward POC.
- Contributing to assay execution, cloning, and general laboratory needs for additional discovery programs as capacity allows.
Benefits
- Compensation reflects the real work you take on.
- Strong co-ops are considered for future opportunities across Flagship and its portfolio companies.
- Enrichment sessions.
- Dedicated professional development track.
- Mentor guidance.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
No Education Listed
