AI Portfolio & Delivery Lead (PM)

Pfizer • New York City, NY

9h • Onsite

About The Position

The AI Portfolio & Delivery Lead is responsible for turning Pfizer Global Supply’s AI-native ambition into sustained operational value across the Global Hospital & Biosimilars manufacturing network. Reporting to the GH&B Operational Excellence & AI Transformation Lead, the role orchestrates the network’s Manufacturing AI Transformation Program, bringing together operational leaders, site teams, Digital experts, and business stakeholders. It translates strategy into action and ensures AI investments produce measurable improvements in safety, quality, supply reliability, productivity, cost efficiency, and colleague effectiveness. The role spans strategic roadmap development and hands-on collaboration with site teams to accelerate deployment, replication, AI fluency, and adoption; success is measured by realized, sustained value.

The position owns the AI roadmap and its end-to-end execution, including prioritization and sequencing of process redesign based on value, feasibility, and network readiness. It works with leaders to refine scope, sequencing, and investment priorities as AI and Digital programs evolve, while tracking delivery and communicating critical updates to leadership. It partners with site AI champions, transformation leads, and business leaders to build engagement, adoption, and capability; sequences interdependent work across squads; and manages solution deployment and replication from pilot through scale.

The role also establishes rigorous value tracking, metrics, program status reporting, and governance. It identifies and resolves risks, roadblocks, and resource conflicts, escalating issues when executive intervention is needed, and chairs governance forums to keep stakeholders informed. The role requires disciplined execution, operational credibility, influence without direct authority, structured problem-solving, and concise communication for senior stakeholders.

The position is on premises, requires up to 25% travel across manufacturing sites, and may involve occasional non-standard work hours to support a global organization. Candidates must be authorized to work in the U.S.; visa sponsorship is not available. Relocation assistance may be available based on business needs and eligibility. The annual base salary range is $162,900 to $271,500, with eligibility for a 20% target bonus under Pfizer’s Global Performance Plan and a share-based long-term incentive program.

Requirements

• Bachelor’s degree and at least 8 years of experience; or a Master’s degree and more than 7 years of experience; or a Ph.D. and at least 5 years of experience.
• Senior manufacturing, automation, or supply chain leader with credible operational experience in a complex manufacturing network.
• Demonstrated record leading large-scale operational or digital transformations, ideally using agile, sprint-based, or other program management models.
• Experience bridging manufacturing operations with digital and AI-enabled capabilities, and communicating credibly with manufacturing and digital leaders.
• Strong program management skills, including prioritizing and delivering multiple initiatives concurrently.
• Ability to carry out work with limited direction.
• Pharmaceutical or life sciences manufacturing background, including working knowledge of GMP and regulated-environment change control.
• Progressive experience in manufacturing operations, transformation, or program leadership, including direct people or matrixed-team leadership.
• Permanent U.S. work authorization; U.S. work visa sponsorship is not available.

Nice To Haves

• Prior exposure to AI/ML-enabled operations in a manufacturing context.
• Experience influencing across matrixed global organizations.
• Lean, Six Sigma, IMEx, or Innovation Coach leadership experience.
• Experience building standards for scaling solutions across multiple sites.
• Experience as a Site AI Champion or in a similar grassroots capability-building role.
• Breadth of diverse leadership experience and capabilities, including influencing and collaborating with peers, developing and coaching others, and guiding colleagues’ work to achieve meaningful outcomes and business impact.

Responsibilities

• Translate the PGS AI-native vision into an actionable, sequenced delivery roadmap for GH&B manufacturing.
• Own end-to-end execution of the AI roadmap, prioritizing process redesign based on value, feasibility, and network readiness.
• Build stakeholder alignment and establish a path from innovation to scaled execution.
• Partner with leadership to refine scope, sequencing, and investment priorities as AI and Digital programs mature.
• Track roadmap value delivery, escalate issues, and provide critical need-to-know communications to leadership.
• Partner with Site AI Champions, Transformation Leads, and business leaders to drive engagement, adoption, and capability building.
• Advance AI fluency and change adoption across the network, helping colleagues use AI tools and new ways of working.
• Sequence interdependent initiatives across squads and opportunities, allocating capacity to high-value work while protecting delivery quality and pace.
• Manage deployment and replication of AI-enabled solutions across sites from pilot through scale, ensuring consistent implementation and rapid time-to-value.
• Track value delivery against the roadmap using quantifiable metrics and maintain a single source of truth for program status.
• Identify, escalate, and drive resolution of risks, roadblocks, and resource conflicts, involving leadership when executive intervention is required.
• Establish and chair governance forums to keep leaders and stakeholders informed and engaged.

Benefits

• 401(k) plan with Pfizer matching contributions and an additional Pfizer retirement savings contribution.
• Paid vacation, holidays, and personal days.
• Paid caregiver, parental, and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligibility for participation in Pfizer’s Global Performance Plan, with a 20% target bonus of base salary.
• Eligibility to participate in a share-based long-term incentive program.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior