Winter Co-op/DMPK Biopharm

GSK Internships & Co-ops powered by Atrium•Upper Providence, PA

8d•$22 - $43•Onsite

About The Position

The GlaxoSmithKline US Drug Metabolism and Pharmacokinetics (DMPK) organization is responsible for delivery of key DMPK support (in vitro, pharmacokinetic, and bioanalytical) to help drive early drug discovery programs. Within that structure, the US discovery in vitro team is responsible for delivering in vitro DMPK results with a focus on high quality and rapid turnaround. A key remit of DMPK organization is to regularly perform a range of standardized enzymology and cellular based in vitro assays to support global in vitro DMPK strategy using both manual and automated assay formats. In addition, the US in vitro group will be exploring opportunities to further optimize current ways of working which will require validation efforts for different assays.

Requirements

Pursuing a degree in Biology, Chemistry, Biomedical Engineering, or similar discipline.
Experience with pipetting.
Must be able to work full-time (35 hours/week) throughout the duration of the 6-month co-op (January ~ June 2027).
Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program.
Post-doctoral candidates are not eligible

Nice To Haves

Track record of good laboratory practices.
Basic understanding of Drug Metabolism, Pharmacokinetic, or Bioanalytical principles.

Responsibilities

Perform standard in vitro DMPK studies including but not limited to intrinsic clearance, protein binding, permeability, etc., in various matrices using both manual and automated assay formats
Work closely with in vitro staff to investigate/validate/implement in vitro DMPK assays to support global in vitro strategy
Assist in optimizing automated assay workflows
Analyze, interpret, and present data to DMPK staff