VP, Program Management

Alnylam Pharmaceuticals•,

11d•$318,800 - $431,200

About The Position

The Vice President, Program Management will play a critical role in advancing programs from Research through Development, Commercialization, and lifecycle management. Program Managers at Alnylam partner with Program Leaders and cross-functional teams to drive strategic execution, manage timelines and key deliverables, identify risks and opportunities, and ensure successful achievement of program milestones and stage gates. The Vice President, Program Management reports to the Head of Pipeline Delivery and leads the global Program Management organization supporting Alnylam's Research, Development, and Commercial portfolios. This leader will drive operational excellence by establishing best practices, standardizing tools and processes, and ensuring consistent, best-in-class program support across the portfolio. The successful candidate will bring deep program management expertise, a strong understanding of the drug development lifecycle, and a proven ability to build high-performing teams. They will provide strategic leadership to optimize portfolio and cross-functional team performance, while fostering a culture of accountability, agility, and continuous improvement. This role requires the ability to balance multiple priorities, navigate complexity, and develop scalable solutions that support Alnylam's evolving business needs.

Requirements

Minimum of 15+ years’ experience in pharmaceutical or biotechnology industry program management, including work on pre-clinical and clinical stage programs
Bachelor’s degree in sciences or related field required, with an Advanced degree (PhD or MBA)
Demonstrated proficiency in program management tools (e.g., Smartsheet, Microsoft Project) and methodology. Knowledge and ability to improve project management tools and skillset through best practices
Strong leadership, problem solving, management and communication skills
Ability to understand program objectives and risks across the entire development and commercialization landscape, so as to provide effective guidance and training to program managers
Excellent interpersonal skills and ability to work effectively with multiple functions
Ability to lead and influence cross functional teams
Self-starter who can manage through ambiguity, learn on the fly, handle multiple priorities, and perform job responsibilities accurately while working in a high energy, deadline-driven, and fast-paced environment
Possess the ability to generate enthusiasm, the ability to quickly gain trust and respect of peers and senior leadership, and have a track record of successfully driving results through strong partnership with others
Sound judgment and discretion in sensitive matters.
Ability to influence without authority.
Thrives in highly entrepreneurial biotech environment and embraces Alnylam’s culture of science, passion and urgency.
Intellectual curiosity, adaptability, and desire to learn and grow to meet the evolving needs of the organization.

Responsibilities

Lead, develop and mentor the group of Program Management professionals spanning research, development, and commercial parts of the business while also being a steward of Alnylam’s core values: Purposeful Urgency, Passion for Excellence, Commitment to People, being Fiercely Innovative, and promoting Open Culture
Leverage extensive drug development experience and strong interpersonal skills to drive operational excellence and establish the value of an effective Program Management function to the company’s success
Establish a proactive and out-reaching approach across Program Leads, department heads and executive team to facilitate communication channels and ensure all programs operational efficiency
In collaboration with department heads and Program Leads, develop an integrated resource plan for each program; conduct analyses, identify gaps, and make recommendations on resource allocation across programs
Assess current Program Management organizational design, infrastructure and work tools to make recommendations on proficiency, standardization and investments required.
Lead and influence within a global matrixed organization and impact decision-making at the highest levels of the organization, while aligning across corporate and business lines
Contribute to, enable and facilitate the development of Program specific annual and long- range corporate objectives, ensuring regular, audience-appropriate communications on status, progress, risks and mitigation efforts to facilitate appropriate discussions
Strategize with program team leadership and other necessary stakeholders to formulate positions and drive alignment process, including in key processes such as the Long-Range Plan and Budget Setting process
Drive overall improvement of and operational consistency across the Program Management team through skill building, best practice development, and applying consistent frameworks across the group
Partner with Alliance Management to coordinate activities and business requirements in support of partnered programs
Provide expertise on organizational effectiveness initiatives including alignment of processes, tools, and technologies that aid in portfolio management across the organization