Visiting Sr. Researcher, Internal Medicine
About The Position
The candidate should be interested in understanding how cellular and molecular heterogeneity develops and impacts on tumor formation, metastatic progression, and therapy. Dr. Kong's laboratory combines fundamental developmental biology tools, such as lineage tracing in genetically engineered mouse models, with bioinformatic approaches, CRISPR screening tools, bioengineered systems, and clinical specimens to study the functional consequences of tumor heterogeneity in pancreatic cancer. The visiting senior researcher will conduct research on the molecular genetics and immunology of a newly discovered genetic disorder. His work will involve a multidisciplinary approach encompassing molecular biology, cell biology, genetics, and immunology. He is expected to analyze whole-exome sequencing data, immunostaining results, confocal microscopy images, single-cell RNA sequencing (scRNA-seq) data, and proteomics datasets. He will perform experiments using human biological specimens and mouse models to investigate the molecular and cellular mechanisms underlying disease pathogenesis.
Requirements
- Terminal degree (Ph.D., M.D.)
- At least 10 years as a Principle Investigator (PI)
- Interest in understanding how cellular and molecular heterogeneity develops and impacts on tumor formation, metastatic progression, and therapy.
- Experience with lineage tracing in genetically engineered mouse models.
- Experience with bioinformatic approaches.
- Experience with CRISPR screening tools.
- Experience with bioengineered systems.
- Experience with clinical specimens.
- Experience with molecular biology.
- Experience with cell biology.
- Experience with genetics.
- Experience with immunology.
- Experience analyzing whole-exome sequencing data.
- Experience analyzing immunostaining results.
- Experience analyzing confocal microscopy images.
- Experience analyzing single-cell RNA sequencing (scRNA-seq) data.
- Experience analyzing proteomics datasets.
- Experience performing experiments using human biological specimens.
- Experience performing experiments using mouse models.
Responsibilities
- Conduct research on the molecular genetics and immunology of a newly discovered genetic disorder.
- Analyze whole-exome sequencing data, immunostaining results, confocal microscopy images, single-cell RNA sequencing (scRNA-seq) data, and proteomics datasets.
- Perform experiments using human biological specimens and mouse models to investigate the molecular and cellular mechanisms underlying disease pathogenesis.
Benefits
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare-no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
