Visiting Grad Student
About The Position
The Lan Lab is dedicated to researching how cancer cells respond to DNA damage through DNA repair mechanisms and developing innovative strategies to target these pathways in cancer therapy. Our significant contributions include uncovering the critical role of PARP in DNA repair, leading to successful applications of PARP inhibitors in the treatment of breast, ovarian, and other types of cancer. We study how DNA responds to oxidative damage at specific chromosomal locations, significantly advancing our understanding of DNA damage response in different chromosomal environments. Furthermore, our recent investigations have revealed a novel mRNA and R-loop-dependent DNA repair pathway that acts as a protective mechanism for the transcribed regions of the genome, introducing a new paradigm in the field of DNA repair research. The incumbent will study the function of immune activation in cancer treatment. They will use established WT and knock out cell lines to examine immune activation and the effects of different inhibitors in cancer therapy.
Requirements
- Student must be engaged in graduate research sponsored by a Duke faculty member.
Nice To Haves
- Strong willingness to learn, adapt, and develop new skills.
- Curiosity and a proactive approach to problem-solving.
- Thrive on doing experimental work.
- Passion for repeatedly conducting detail-oriented experiments with a focus on precision and efficiency.
- Self-motivated and dedicated to continuous improvement.
- Ability to communicate effectively within a team and contribute to a collaborative research environment.
Responsibilities
- Study function of immune activation in cancer treatment.
- Use established WT and knock out cell lines to examine immune activation and effects of different inhibitors in cancer therapy.
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What This Job Offers
Career Level
Entry Level
Education Level
Associate degree
