Vice President, Strategic Purchasing & Purchasing

Stoke Therapeutics•Bedford, MA

11h•$227,000 - $345,000•Hybrid

About The Position

Stoke Therapeutics is a biotechnology company focused on restoring protein expression through RNA medicine. Their proprietary TANGO approach uses antisense oligonucleotides (ASOs) to restore natural protein levels. The company is developing zorevunersen for Dravet syndrome and is initially focusing on central nervous system and eye diseases caused by haploinsufficiency. Stoke is headquartered in Bedford, Massachusetts.

Requirements

Minimum of 15 years of relevant strategic sourcing, procurement, vendor management, finance, or operations experience, including significant leadership experience in the pharmaceutical, biotechnology, or life sciences industry.
Demonstrated success building and scaling an enterprise procurement function in a high-growth clinical development environment; commercialization readiness or commercial-stage experience required.
Enabled companywide savings through outsourcing-led initiatives over both short- and long-term periods.
Bachelor’s degree required; advanced degree or relevant professional certification preferred.
Executive-level understanding of drug development, clinical trials, CRO oversight, clinical supply chain, manufacturing, quality, regulatory expectations, and commercial readiness considerations.
Proven ability to influence senior leaders, lead cross-functional decision-making, and balance enterprise priorities across cost, quality, speed, risk, innovation, and compliance.
Extensive experience leading complex supplier negotiations and advising on material contract terms, business implications, risk allocation, service levels, performance obligations, and governance structures.
Strong financial and analytical acumen, including spend analysis, value creation, budgeting, forecasting, KPI development, and executive-level reporting.
Experience selecting, implementing, or optimizing procurement processes, systems, contract lifecycle tools, purchase-to-pay workflows, and internal control frameworks.
Track record of building and leading high-performing teams, developing talent, and creating scalable operating models in dynamic, fast-paced environments.
Excellent executive communication skills, including the ability to distill complex issues, present recommendations, and drive alignment with senior management and cross-functional stakeholders.

Nice To Haves

Advanced degree or relevant professional certification preferred.

Responsibilities

Establish and lead the enterprise strategic sourcing and procurement function, including the operating model, governance structure, policies, systems, controls, and performance expectations required to support a growing clinical-stage and potentially commercial biotechnology company.
Serve as a strategic partner to the executive team and functional leaders, advising on sourcing strategy, supplier risk, contracting priorities, spend optimization, and vendor capabilities needed to advance corporate objectives.
Lead complex, high-value RFPs/RFQs/RFIs and supplier selection processes in partnership with business stakeholders, legal, finance, quality, and compliance.
Oversee negotiation strategy for material agreements, ensuring favorable commercial terms, appropriate risk allocation, scalability, and alignment with business priorities.
Build and manage a strategic supplier relationship management program, including executive-level vendor engagement, performance scorecards, issue escalation, corrective action planning, and lifecycle governance.
Lead enterprise spend visibility and analytics, identifying opportunities for cost avoidance, savings, process efficiency, consolidation, risk mitigation, and improved forecasting.
Partner with Finance and functional leaders to strengthen budget discipline, purchase-to-pay processes, contract lifecycle management, and alignment between sourcing decisions and financial planning.
Establish key procurement metrics and executive reporting to monitor performance, compliance, value creation, supplier concentration, risk, and continuous improvement opportunities.
Ensure procurement practices comply with applicable laws, regulations, company policies, quality expectations, and internal control requirements.
Build, mentor, and scale a high-performing procurement team, fostering business partnership, accountability, continuous improvement, and a service-oriented culture.
Partner with IT team to implement financial systems that enable better financial controls and spend management.
Maintain external awareness of market trends, supplier dynamics, technology innovation, and procurement best practices relevant to biotechnology, clinical development, and commercialization.