Upstream Associate

Sino Biological, Inc.•Houston, TX
•$30 - $50•Onsite

About The Position

This entry-level, hands-on role combines upstream bioprocessing and protein quality control. The Associate supports recombinant protein and antibody expression using mammalian cell cultures and QC testing to evaluate product quality. Working closely with project scientists, the role contributes to aseptic cell culture, transfection, harvesting, and analytical testing, with an emphasis on accuracy, documentation, and cross-team collaboration. The schedule is part-time, Saturday and Sunday for 8 hours, with potential for a full-time hire. Flexibility is important, including potential weekend work, early or late weekday shifts, and participation in lab maintenance or cross-functional support as needed.

Requirements

  • Bachelor’s degree (BA or BS) in Biology, Cell Biology, Biochemistry, Biotechnology, or a related field.
  • Laboratory experience with mammalian cell culture; HEK293 and CHO experience is required.
  • Familiarity with suspension culture and aseptic techniques.
  • Strong attention to detail, documentation, and troubleshooting skills.
  • Flexibility and adaptability to varying schedules or project demands.
  • Effective communication skills and ability to work collaboratively in a team-oriented environment.
  • Ability to lift and move 25–50 lbs as needed.

Nice To Haves

  • Basic experience with analytical assays such as SDS-PAGE, HPLC-SEC, UV-Vis, or endotoxin testing.

Responsibilities

  • Perform recombinant protein expression using mammalian systems such as HEK293 and CHO.
  • Execute upstream workflows including cell thawing, expansion, transfection, and harvesting.
  • Maintain lab cleanliness, including biosafety cabinets, incubators, and shared spaces.
  • Handle and maintain cell cultures using proper aseptic techniques.
  • Conduct protein quality control assays, including SDS-PAGE, HPLC-SEC, endotoxin testing, and UV-Vis measurements.
  • Record data and observations accurately and promptly in electronic lab notebooks.
  • Assist with media and reagent preparation, equipment setup, and maintenance tasks.
  • Support instrument calibration, troubleshooting, and lab upkeep.
  • Collaborate with downstream and cross-functional teams to ensure smooth project execution.
  • Conduct product aliquoting to meet delivery timelines.
  • Adhere to safety and PPE protocols under federal, state, and local regulations.

Benefits

  • Free onsite parking.
  • Free onsite gym.
  • Career growth opportunities and learning from industry professionals.
  • Supportive team culture that values diversity, collaboration, and professional development.
  • Work at a brand-new, state-of-the-art facility designed for collaboration and scientific excellence.
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