Temporary Extra Worker-Research Lab

University of Pennsylvania Perelman School of Medicine • Philadelphia, PA

5d • Onsite

About The Position

This temporary research position in The Center for Cellular Immunotherapies will focus on establishing a base edited platform for armoring CAR to overcome the major suppressive elements found in the tumor microenvironment which hinder long term efficacy of T cell immunotherapies. The second study focus involves enhancing the delivery of lentiviral immunotherapies to broaden accessibility of therapies to patients and lower their cost to patients.

Requirements

• Bachelors degree
• 1 years experience working in a research lab with focus on immunology.

Responsibilities

• Screen and evaluate the designs and performance of targeted delivery lentiviral vectors in in vitro and in vivo studies.
• Resulting data will be evaluated and presented.
• Establish armored platform for CAR T cells via base editing of multiple receptors involved in suppressing immunotherapies from signals generated from tumor microenvironment.
• Establish protocol for multi-faceted armoring to be used in both constitutive and “And -Gated” CAR T cells.
• Evaluate performance in in vitro and in vivo studies, evaluating and presenting data.

Benefits

• Health and Life: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare.
• Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard. Please note that benefit eligibility is determined/based on ACA guidelines.

What This Job Offers

• Career Level: Entry Level