Technical Development Senior Associate Scientist

RocheSouth San Francisco, CA
$92,600 - $172,000Onsite

About The Position

We are seeking a creative, enthusiastic, and highly motivated researcher to develop cell lines expressing antibodies or other therapeutic molecules and improve cell line development processes. The successful candidate will learn stable CHO cell line development (CLD) for clinical and commercial manufacturing using Genentech’s industry-leading targeted integration (TI) expression technology. The candidate will be responsible for CLD, improving targeted integration efficiency, and help with streamlining and improving TI CLD platform processes. Familiarity with cell culture and stable cell line generation is preferred. A strong background in cell and molecular biology is required. This is an ideal position for a researcher who is enthusiastic about research, innovation, and gaining drug development experience. As such the position requires excellent communication skills and the desire to learn about and integrate multiple aspects of drug development. The selected individual is expected to work independently with minimal supervision to design and execute different experiments in parallel.

Requirements

  • B.S. or M.S. with 2+ years of experience in molecular biology, cell biology, biochemistry or other related disciplines.
  • Expertise in molecular and cell biology including DNA and cell manipulation.
  • Expertise in gene copy number analysis.
  • Skilled in communication and presentation.
  • Ability to clearly convey complex ideas and data both verbally and written.
  • Strong work ethic.
  • Ability to work well with others.
  • Robust problem-solving skills.

Nice To Haves

  • Familiarity with cell culture and stable cell line generation.
  • Familiarity with automation.

Responsibilities

  • Develop cell lines expressing antibodies or other therapeutic molecules.
  • Improve cell line development processes.
  • Perform stable CHO cell line development (CLD) for clinical and commercial manufacturing using targeted integration (TI) expression technology.
  • Improve targeted integration efficiency.
  • Streamline and improve TI CLD platform processes.
  • Design and execute different experiments in parallel with minimal supervision.

Benefits

  • Discretionary annual bonus may be available based on individual and Company performance.
  • Benefits detailed at the link provided below.
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