Senior Associate Scientist - Process Development

Pfizer • Pearl River, NY

1d • Onsite

About The Position

As a Senior Associate Scientist within the Early Bioprocess Development (EBPD) group in the Vaccines organization, you will apply cutting-edge technologies to accelerate the development of high-quality protein subunit vaccines. This role is highly technical and collaborative, requiring deep hands-on expertise in molecular biology, cell culture, and data-driven process optimization. Collaborating with multi-disciplinary teams and working closely with the cell culture, purification, mRNA production and analytical groups. Maintain impeccable, timely records in Electronic Laboratory Notebooks (ELNs) and author comprehensive technical/production reports. Draft, review, and contribute to internal technical reports and external scientific publications. Contribute to building a culture that embraces excellence, urgency, partnerships with key stakeholders, continuous learning and improvement, increasing technical skill base and other cross-functional expertise. Ensure all tasks and responsibilities are carried out according to scientific, ethical and regulatory standards.

Requirements

• B.S. degree with 3 to 5 years of relevant industry or research experience, or M.S. in bioengineering, biochemistry, chemical engineering or related fields with 0 to 3 years of experience
• Experience in aseptic cell culture techniques, including cell passaging and maintenance, transfection, monitoring cell morphology and viability.
• Experience in using flow cytometry, and cell sorting cytometers as well as flow cytometry analysis software such as FlowJo.
• Knowledge and hands-on experience in molecular biology techniques including DNA/RNA extraction, PCR, ddPCR, RT-PCR, ligation, cloning, transformation, gel electrophoresis, SDS-PAGE, western blot, ELISA.
• Well organized, self-motivated, team-oriented with high attention to detail.
• Strong collaborative spirit and communication skills.
• Permanent work authorization in the United States.

Nice To Haves

• Experience in setting up, feeding, sampling and controlling benchtop or single-use bioreactors (batch, fed-batch)
• Hands-on knowledge and experience with NGS sequencing platforms.

Responsibilities

• Optimize cell line development workflows to improve subunit protein expression, overall productivity, process efficiency and biological robustness of the production systems
• Execute fermentation to characterize key performance indicators including cell fitness, growth, recovery, protein production yield, protein purity etc.
• Perform data analysis to identify patterns, establishing quantitative correlations between input parameters such as DNA sequences and output values such as protein yield and quality.
• Present experimental data and strategic conclusions at cross-functional meetings, contributing to team-wide knowledge sharing.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior