Synthetic DNA Process Development Scientist

Eurofins USA Clinical DiagnosticsLouisville, KY
Onsite

About The Position

Eurofins Scientific is an international life sciences company providing a unique range of analytical testing services. This role focuses on developing, optimizing, and scaling chemical processes for high-throughput and high-quality oligonucleotide production. The position is for a highly skilled and motivated Organic Chemist with expertise in oligonucleotide synthesis and purification to support process development and manufacturing.

Requirements

  • Ph.D. or Master’s degree in Organic Chemistry or related field (required)
  • Minimum 5 years of industrial experience in chemical synthesis
  • Experience with solid-phase oligonucleotide synthesis
  • Experience in oligonucleotide purification process development
  • Strong analytical skills (HPLC, LC-MS)
  • Experience scaling processes to manufacturing

Nice To Haves

  • Experience in GMP or regulated environments
  • Familiarity with automated DNA/RNA synthesizers
  • Knowledge of modified nucleotides
  • Experience in high-throughput oligo production

Responsibilities

  • Design, develop, and optimize chemical synthesis processes for nucleotides and oligonucleotides
  • Process development and scale-up from R&D to manufacturing
  • Develop and improve oligonucleotide purification processes (e.g., HPLC, ion-exchange, desalting)
  • Troubleshoot synthesis and purification challenges to improve yield and purity
  • Collaborate with manufacturing, QC, and engineering for process transfer
  • Evaluate new chemistries and technologies
  • Author SOPs, batch records, and technical reports
  • Ensure compliance with quality systems
  • Mentor lab technicians

Benefits

  • comprehensive medical coverage
  • dental
  • vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Number of Employees

5,001-10,000 employees

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