Stem Cell Research Scientist

Vertex Inc.•Boston, MA

1d•$104,200 - $156,200•Onsite

About The Position

The Stem Cell Research Scientist works with some independence and is adept at conceptually outlining studies to design and execute focused research projects or a series of complex experimental procedures including the development of human hematopoietic cell models and assays to evaluate targets and lead molecules for Vertex diseases. Completes work in a resourceful, self-sufﬁcient manner and is able to design alternative approaches to achieve desired outcomes. Keeps current on the scientiﬁc literature relevant to scientiﬁc methodology or ﬁeld(s) of technical expertise. This level captures both the Research organization’s entry level for staff with a research doctoral degree (PhD) and the advanced experimental expert leading one or more critical laboratory functions with high impact on drug discovery projects.

Requirements

Ability to design and execute complex experiments including the development of human hematopoietic cell assays to evaluate targets and lead molecules for Vertex diseases
Must have hands-on experience working with primary human hematopoietic cells and have experience developing and running multicolor flow cytometry and cell-based functional assays
Experience with gene editing techniques
Demonstrates astute understanding of own discipline and the relevant literature
Maintains a high level of knowledge related to current developments in the scientiﬁc Project ﬁeld
Displays proven productivity and experimental creativity, and effective dissemination of ideas
Demonstrates effective, self-sufﬁcient communication skills, especially in peer-directed presentations
Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas

Responsibilities

Designs and conducts elaborate, conceptually connected, multi-component in vitro and ex vivo experiments with primary hematopoietic cells and cell lines
Collates and interprets data systematically, and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities
Exercises solid judgment to prioritize studies, considering feasibility and Project impact
Performs advanced experimental troubleshooting
Scours relevant scientiﬁc literature and routinely incorporates new insights into research activities
Identiﬁes, prioritizes and introduces relevant emerging technologies in ﬁeld of expertise to advance the existing technology platforms and create/maintain a competitive advantage
Explores the feasibility of applying new scientiﬁc principles/concepts or implements and validates new experimental approaches and technologies to achieve project goals
Contributes to patent and/or publication preparation
Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings
Performs other duties as assigned