Staff Scientist

Fred Hutchinson Cancer Center•Seattle, WA

12d

About The Position

The Cohn Laboratory in the Vaccine and Infectious Disease Division at Fred Hutchinson Cancer Center studies how human immunity is established, maintained, and remodeled by infection over a lifetime. The laboratory investigates differences in individuals’ ability to control infection and how immune memory is shaped by age and repeated exposure, using laboratory techniques and computational analyses to characterize hosts and pathogens. The Staff Scientist will lead studies of human immune memory and immune control in longitudinal cohorts. The position is responsible for designing, executing, and analyzing high-resolution sequencing and single-cell immune profiling of clinical samples. The Staff Scientist will take primary scientific responsibility for one or more cohort studies, develop methods to extend the laboratory’s sequencing approaches to new pathogens and immunology questions, mentor graduate students and technical staff, and contribute to manuscripts and grant applications as a senior author and co-investigator. The position reports directly to Dr. Cohn.

Requirements

Ph.D. or M.D. in Immunology or a related field.
Evidence of independent research and a strong publication record.
Experience with molecular biology, cloning, PCR/qPCR, next-generation sequencing, and single-cell assays, including downstream data analysis.
Experience designing and conducting multi-color flow cytometry.
Proficiency with relevant computer programs or languages, including FlowJo and/or another flow-analysis program, and Python and/or R for statistical analysis.

Nice To Haves

Excellent oral and written communication and problem-solving skills.
Motivation, adaptability, and a keen interest in infectious disease and immunology.
A strong background in collaborative team leadership, positive communication, and project completion.
Willingness to work with biohazardous materials, such as HIV-1, and rare human samples.
Curiosity and initiative to learn new techniques, exceptional organizational and communication skills, creativity and innovation in experimental design, and comfort with a leadership role.

Responsibilities

Lead the development and conduct of assays to assess immune responses, including high-dimension multiparameter flow cytometry, FACS sorting, molecular biology, genomics, and single-cell assays.
Supervise, mentor, and train less experienced laboratory members.
Coordinate data analysis, including work with tight timelines, for scientific publications and presentations.
Establish new technologies in the laboratory.
Prepare and/or review experimental procedures, assay plans, reports, and related documents.
Interface with collaborating researchers and participate in formal and informal sharing of data.
Contribute to grant applications, progress reports, and manuscripts.
Present data at meetings and conferences.
Perform other duties and projects as assigned.