UNIV - Staff Scientist II - Department of Pathology & Laboratory Medicine

Medical University of South Carolina•Charleston, SC

3d•Onsite

About The Position

The Staff Scientist II position requires a PhD and at least four years of postdoctoral experience. The candidate is expected to manage multiple projects with minimal PI input, contribute intellectually to project development, and implement effective approaches for accomplishing the PI’s research objectives. This role also involves developing new research methodologies and models, preparing manuscripts for publication, and presenting research findings at national meetings. The position is within the Department of Pathology & Laboratory Medicine and the South Carolina Alzheimer’s Disease Research Center (SC-ADRC). This is a non-tenure track position, with renewal dependent on continued availability of extramural funding. Salary is commensurate with experience.

Requirements

PhD with considerable experience in biochemistry and molecular biology techniques.
Knowledge of cardiovascular diseases, neurofibromatosis, peripheral nerve sheath tumors, and neurodegenerative diseases.
Demonstrate a publication record in all the above fields.
Excellent written and verbal communication skills.
Eligible for employment in the U.S.
Ability to perform job functions in an upright position (Continuous).
Ability to perform job functions in a seated position (Continuous).
Ability to perform job functions while walking/mobile (Frequent).
Ability to climb stairs (Infrequent).
Ability to work indoors (Continuous).
Ability to work in all cold temperature extremes, i.e. spot coolers (Frequent).
Ability to bend at the waist (Frequent).
Ability to twist at the waist (Frequent).
Ability to perform 'pinching' operations (Continuous).
Ability to fully use both hands/arms (Continuous).
Ability to perform repetitive motions with hands/wrists/elbows and shoulders (Continuous).
Ability to fully use both legs (Continuous).
Ability to reach in all directions (Continuous).
Possess good finger dexterity (Continuous).
Ability to maintain tactile sensory functions (Continuous).
Ability to maintain good olfactory sensory function (Continuous).
Ability to lift and carry 30 lbs., unassisted (Frequent).
Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted (Frequent).
Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted (Frequent).
Ability to push/pull objects, up to 50 lbs., unassisted (Infrequent).
Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings (Frequent).
Ability to maintain 20/40 vision, corrected (Continuous).
Ability to see and recognize objects close at hand (Continuous).
Ability to see and recognize objects at a distance (Continuous).
Ability to match or discriminate between colors (Continuous).
Ability to determine distance/relationship between objects; depth perception (Continuous).
Good peripheral vision capabilities (Continuous).
Ability to maintain hearing acuity, with correction (Continuous).
Ability to perform gross motor functions with frequent fine motor movements (Continuous).
Ability to be qualified physically (by medical personnel) for respirator use, initially and annually.
Ability to work alone in isolated areas, such as darkrooms (Frequent).
Ability to obtain and maintain a valid drivers license.
Computer literacy.
Ability to work rotating shifts as required.
Ability to work overtime as required.
Ability to learn and use new processes, tools and equipment as required.

Nice To Haves

Preferential consideration will be given to applicants with the above-mentioned background.

Responsibilities

Develop an independent research project in consultation with the PI (30%): Develop independent research projects in alignment with the PI's goals, including reviewing scientific literature, maintaining meticulous laboratory records, and presenting results to PI. Responsible for drafting and publication of results in leading scientific journals and assisting with research grant proposals.
Extensive work using in vitro human and murine peripheral nervous system cancer cell lines and in vivo animal models.
Genetically engineered murine animal model breeding and MPNST xenograft pre-clinical trial studies using intraperitoneal, subcutaneous, and/or oral gavage delivery of therapeutics.
Draft, edit, and publish high-impact manuscripts and maintain standardized protocols for experimental techniques and equipment operation.
Present data at lab meetings and scientific conferences.
Collaborate closely with the PI to write, edit, and develop external research grant proposals for federal (NIH, DoD) and private organizations.
Training and supervision of technical staff, graduate students, and other laboratory personnel (10%).
Oversight of daily lab needs, activity and budgeting, including maintaining databases of laboratory reagents, cell lines, and ordering supplies.
Mentoring students: undergraduate, graduate, medical students, postdocs and visiting scholars.
Supervise, advise, and mentor graduate students, postdoctoral fellows, and technical staff on experimental design and approach.
Lab Management (20%): Manage daily laboratory needs, chemical/cell line databases, safety compliance, and budgeting.
Oversee inventory, prepare electronic supply orders, and coordinate the maintenance of equipment and glassware.
Maintain IRB protocols, IBC, IACUC protocols and other laboratory protocols as needed.
Community Outreach and Grant-related Development (30%): Engage the community to develop ADRC-related relationships through lectures on neurodegeneration initiatives.
Attend local community wellness workshops/expos.
Create a family guide to serve as educational and resource materials for caregivers and patients.
Work to define objectives and themes for the local SC-ADRC symposium.
Develop an agenda for the symposium, recruit/invite guest speakers, maintain a budget, organize food, develop content for program booklet, obtain sponsor and promote the event.
Community Education (10%): Create presentations and lectures about developing neurodegeneration initiatives.
Interact with local youth by providing educational lectures to supplement local education standards.