Staff Scientist I - Stem Cell Core
About The Position
The Lieber Institute for Brain Development (LIBD) is seeking a highly skilled and collaborative Staff Scientist with significant experience in human induced pluripotent stem cells (hiPSCs) and iPSC-derived neuronal models to join the Stem Cell Core. This position is open to stem cell biologists seeking a role within a translational research setting with a focus on hiPSC-based modeling of neurodevelopmental and neuropsychiatric disorders. This position is housed within a team that establishes and maintains cell line resources and develops and implements hiPSC differentiation protocols into various brain cell types. The staff member will also contribute to ongoing, team-based research projects as part of mission-relevant Institute initiatives. Candidates should have extensive training in hiPSC culture and hiPSC-based neuronal modeling, and experience in disease modeling with large cohorts of iPSC lines is highly desirable. Responsibilities include cell culture, wet bench experiments, and data collection and analysis, as well as assisting with day-to-day Stem Cell Core management and scientific communication.
Requirements
- Ph.D. in cell and molecular biology, neuroscience, or a closely related field
- Cellular and molecular biology experience
- Significant experience (3+ years) in hiPSC-derived neuronal culture and/or brain disease modeling
- Strong troubleshooting skills and ability to independently resolve technical challenges
- Excellent communication and collaborative skills, with ability to work effectively in a team-based environment
Nice To Haves
- hiPSC-derived brain organoid culture
- Genome engineering of hiPSCs and derived cell types
- Single-cell or spatially-resolved transcriptomic analysis
- Experience in a project of disease modeling with a large cohort of hiPSC lines
Responsibilities
- Perform all aspects of experiments related to hiPSC-based neuronal and disease models, including hiPSC reprogramming, culture, differentiation, and data collection and analysis
- Maintain detailed experimental records and ensure reproducibility of protocols
- Assist in postmortem dural fibroblast culture
- Assist in preparing cell materials upon request from internal and external researchers
- Assist with records, reports, filing, and chart maintenance for management of cell line repository as assigned
- Provide technical training and experimental design support to internal researchers for stem cell-related projects
- Effectively communicate with researchers to support cross-institute collaborative projects
- Other duties as assigned
Benefits
- Competitive, comprehensive benefits package
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
