Staff Scientist I - Stem Cell Core
About The Position
The Lieber Institute for Brain Development (LIBD) is seeking a highly skilled and collaborative Staff Scientist with significant experience in human induced pluripotent stem cells (hiPSCs) and iPSC-derived neuronal models to join the Stem Cell Core. This position is ideal for stem cell biologists looking for a role in a translational research setting focused on hiPSC-based modeling of neurodevelopmental and neuropsychiatric disorders. The role involves establishing and maintaining cell line resources, developing and implementing hiPSC differentiation protocols into various brain cell types, and contributing to ongoing, team-based research projects. Candidates should possess extensive training in hiPSC culture and hiPSC-based neuronal modeling, with experience in disease modeling using large cohorts of iPSC lines being highly desirable. Responsibilities include cell culture, wet bench experiments, data collection and analysis, assisting with Stem Cell Core management, and scientific communication.
Requirements
- Ph.D. in cell and molecular biology, neuroscience, or a closely related field
- Cellular and molecular biology experience
- Significant experience (3+ years) in hiPSC-derived neuronal culture and/or brain disease modeling
- Strong troubleshooting skills and ability to independently resolve technical challenges
- Excellent communication and collaborative skills, with ability to work effectively in a team-based environment
Nice To Haves
- hiPSC-derived brain organoid culture
- Genome engineering of hiPSCs and derived cell types
- Single-cell or spatially-resolved transcriptomic analysis
- Experience in a project of disease modeling with a large cohort of hiPSC lines
Responsibilities
- Perform all aspects of experiments related to hiPSC-based neuronal and disease models, including hiPSC reprogramming, culture, differentiation, and data collection and analysis
- Maintain detailed experimental records and ensure reproducibility of protocols
- Assist in postmortem dural fibroblast culture
- Assist in preparing cell materials upon request from internal and external researchers
- Assist with records, reports, filing, and chart maintenance for management of cell line repository as assigned
- Provide technical training and experimental design support to internal researchers for stem cell-related projects
- Effectively communicate with researchers to support cross-institute collaborative projects
- Other duties as assigned
Benefits
- Competitive, comprehensive benefits package
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
