Sr. Scientist, Mass Spectrometry

Merck • Upper Gwynedd Township, PA

1d • $117,000 - $184,200 • Onsite

About The Position

The Analytical Enabling Capabilities organization is seeking a motivated scientist with technical expertise in mass spectrometry-based protein, protein conjugation or oligonucleotides or polysaccharide characterization. In addition to mass spectrometry skills, candidates with strong proteomics and data science skills are also sought. The successful candidate will independently conduct mass spectrometry experiments to support multiple vaccines programs, represent the team in cross-functional teams, and develop new methods to solve current industry challenges. This role involves documenting experiments in electronic laboratory notebooks, authoring summaries for stakeholders, and presenting at seminars and publishing in scientific journals. The candidate will also participate in optimizing sample preparation, data processing, and reporting strategies.

Requirements

• Ph.D. in Analytical Chemistry or Biological Sciences in the field of mass spectrometry
• Experience conducting mass spectrometry and proteomics experiments, including sample preparation and optimization, mass spectrometer operation and maintenance, and data interpretation and analysis.
• Experience with Thermo, Waters, and Sciex instruments.
• Familiarity with Genedata or other biopharma MS software.
• Excellent verbal and written communication skills, as demonstrated through high impact scientific publications and presentations.

Nice To Haves

• Candidates with a MS degree and 4+ years, or BS degree and 7+ years of relevant experience will also be considered.
• Experienced in higher order structure MS or proteomics
• Familiarity with electronic laboratory notebook applications and good documentation practices.
• Good understanding of vaccines development.
• Experience characterizing vaccines or recombinant proteins.
• Experience with protein conjugation, oligonucleotides or polysaccharide characterization.
• Familiarity with R programming language for data processing, statistics and visualization.

Responsibilities

• Perform LC-MS based assays including peptide mapping, intact mass, native mass spectrometry, proteomics, higher order structure, and host cell protein analysis or oligonucleotides or polysaccharide characterization for vaccines programs.
• Represent the mass spectrometry group in project teams.
• Author technical reports and scientific presentations.
• Explore and develop new technologies applicable to our field.
• Perform data processing with Genedata or other biopharma data interpretation software.
• Demonstrate effective multitasking, prioritization and problem-solving skills in the planning and execution of experiments.

Benefits

• medical, dental, vision healthcare and other insurance benefits (for employee and family)
• retirement benefits, including 401(k)
• paid holidays
• vacation
• compassionate and sick days
• annual bonus
• long-term incentive

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree