Associate Scientist - Analytical & Bioanalytical Mass Spectrometry (ABMS)

Regeneron Pharmaceuticals•Tarrytown, GA

1d•$93,900 - $153,300•Onsite

About The Position

Regeneron Pharmaceutical's Analytical and Biological Mass Spectrometry Group (ABMS), located in Tarrytown, NY is seeking a motivated Associate Scientist to join our fast-paced and interdisciplinary team working on analytical and bioanalytical development on novel siRNA/oligonucleotide-based modalities in a diverse genetic medicine pipeline.

Requirements

BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field
0–3 years of relevant hands‑on laboratory experience in analytical chemistry or bioanalytical sciences
Strong hands-on experience with liquid chromatography (such as reversed-phase, size-exclusion, ion exchange chromatography) is essential, particularly HPLC or UPLC techniques
Comfortable working independently after initial guidance
Able to communicate effectively about technical challenges and results

Nice To Haves

Hands-on experience with various types of biological matrices
Hands-on experience with fractionation, solid phase extraction and/or hybridization techniques
Mass spectrometry experience is beneficial
Mentally flexible and adapt quickly to changing priorities in a fast-paced environment
Excellent team player who can follow directions while also bringing own insights to problem-solving
Growth mindset and eagerly embrace new challenges and learning opportunities
Interested in learning about genetic medicines and development for impactful RNA-based therapies

Responsibilities

Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates and monoclonal antibodies (mAbs)
Perform analytical testing and sample preparation of siRNA/oligonucleotides with a focus on chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and other mass spectrometry related methods
Independently conduct sample preparation and LC-MS analyses in compliance with SOPs or drafted protocols, and document experimental procedures and results in electronic laboratory notebook (ELN)