Sr Scientist I Pharmacology

AbbVie • North Chicago, IL

1d

About The Position

Drive the discovery of innovative therapies and treatments for obesity by designing and executing creative experimental strategies grounded in molecular pharmacology, with emphasis on GPCR signaling, trafficking, and efficacy. Lead efforts to develop and optimize advanced in-vitro biochemical and cell-based assays to produce high-quality data with direct translational impact. Propel scientific innovation in GPCR pharmacology and obesity research by fostering robust, cross-functional collaborations, integrating multidisciplinary expertise, and leveraging technological advancements to accelerate drug discovery.

Requirements

• Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Degree in Pharmacology, Cell Biology, Biochemistry, or related discipline (preferred), with relevant post graduate experience.
• Familiarity with quantitative assay development, data analysis, and interpretation in drug discovery.
• Demonstrated ability to think independently, troubleshoot, and lead projects.
• Demonstrated ability to thrive in a fast-paced, cross-functional, and dynamic environment, function independently, communicate effectively, and collaborate closely with others.

Nice To Haves

• Experience in obesity, metabolic, or related disease area research is strongly preferred.
• Experience with laboratory automation and high-throughput screening is a plus.

Responsibilities

• Demonstrate scientific initiative and creativity in GPCR pharmacology research and development activities.
• Independently develop and validate cell-based and biochemical assays to characterize GPCRs.
• Apply advanced techniques to assess biased agonism, receptor internalization, trafficking, and signaling pathway modulation.
• Utilize high-throughput screening methods to identify novel GPCR modulators.
• Implement emerging technologies, such as biosensor assays and CRISPR-based gene editing, for assay development.
• Analyze and interpret complex data to draw conclusions and inform decision-making.
• Collaborate with cross-functional teams, including chemists, to support obesity research projects and SAR analyses.
• Maintain accurate and detailed records of experiments and results and adhere to corporate safety and compliance standards.
• Serve as primary author for scientific and regulatory reports and present findings to appropriate stakeholders.

Benefits

• paid time off (vacation, holidays, sick)
• medical/dental/vision insurance
• 401(k)
• short-term incentive programs

What This Job Offers

• Job Type: Full-time
• Career Level: Senior