Sr. Manager/Associate Director, Medical Affairs

BridgeBio Pharma

1d•$165,000 - $210,000

About The Position

The Senior Manager/Associate Director, Medical Affairs reports to the Executive Director, Skeletal Dysplasia, and helps execute Medical Affairs activities across the skeletal dysplasia portfolio. This hands-on individual-contributor role has primary responsibility for medical review and MLR submissions, scientific content development, advisory boards and company-sponsored symposia, Medical Information support, exploratory analyses of existing data and data-generation opportunities, and external agency deliverables. The role independently drives assigned workstreams from development through approval and execution while partnering with Medical Directors and functional leads on scientific and strategic decisions. The role may be hybrid, with in-office collaboration two to three days per week in the San Francisco office, or U.S.-based remote with quarterly or as-needed visits to that office. Travel of up to 50% is expected for scientific congresses, advisory boards, company-sponsored symposia, KOL engagements, and key internal meetings.

Requirements

A PharmD, PhD, genetic counseling degree, NP/advanced practice degree, MS, or another relevant advanced scientific or healthcare degree.
Typically 3–5 years of pharmaceutical or biotechnology Medical Affairs experience, including hands-on medical review and MLR submissions, scientific content development, and advisory board or symposium execution.
Candidates with an MS or similar degree should have at least 5 years of demonstrated pharmaceutical or biotechnology Medical Affairs experience.
Candidates with a PharmD or PhD may qualify with less industry experience if supported by a Medical Affairs fellowship or equivalent.
Strong project-management and organizational skills, including the ability to independently manage multiple complex workstreams and deadlines.
Strong scientific writing and communication skills and exceptional attention to detail.
Working knowledge of clinical trial data and basic biostatistical concepts, with the ability to help frame analysis questions, interpret outputs, and summarize findings accurately.
Ability to distinguish executional decisions that can be managed independently from scientific or strategic issues requiring escalation.
Ability to travel as needed and legal authorization to work in the United States.

Nice To Haves

Experience in pediatric rare disease, genetics, skeletal dysplasia, or launch-stage Medical Affairs is preferred but not required.

Responsibilities

Review scientific and medical materials for scientific accuracy, appropriate interpretation of clinical data, consistency with source documentation, and alignment with approved scientific communications; escalate clinical interpretation or strategic-positioning questions to the responsible Medical Director.
Initiate, submit, and manage Medical Affairs materials through MLR review, including preparing submissions and references, incorporating reviewer comments, maintaining version control, resubmitting, and tracking materials through final approval.
Partner with the Medical Information lead to identify new or updated response-material needs and review Medical Information letters for scientific accuracy, data interpretation, and consistency with current evidence.
Support development and revision of Medical Information content with the Medical Information lead and relevant subject-matter experts.
Manage execution of Medical Affairs advisory boards, including advisor coordination, timelines, pre-read materials, meeting logistics, agency management, MLR review, and post-meeting deliverables.
Work with Medical Directors to develop advisory board objectives, agendas, discussion questions, presentations, and scientific content.
Support development and execution of company-sponsored scientific symposia, coordinating with Medical Directors, external faculty, and KOLs on presentations, scientific content, faculty review, MLR submission, revisions, and finalization.
Support Medical Directors and Clinical Development in exploring and conducting analyses of clinical trial, natural history, and real-world data, including framing analysis questions, coordinating with Biostatistics and Data Management, and summarizing results for internal review and scientific communications.
Help identify and evaluate data-generation opportunities such as investigator-initiated studies, registries, chart reviews, and real-world evidence collaborations by supporting data-gap assessments, preparing concept summaries, and coordinating cross-functional input.
Manage day-to-day relationships with Medical Affairs agencies and external vendors; partner with Medical Operations on contracts, statements of work, purchase orders, and approvals, and manage vendor timelines, deliverables, meetings, revisions, and execution.
Track project milestones, risks, dependencies, and budgets with Medical Operations and functional leads, and proactively identify and resolve execution issues.
Partner across Medical Affairs, Scientific Communications, Field Medical/MSL, Medical Information, Clinical Development, Regulatory, Legal, Medical Operations, and other functions to execute priority initiatives.

Benefits

Market-competitive compensation, annual performance bonus, and company equity.
401(k) with employer match.
Employee Stock Purchase Program (ESPP).
Pre-tax commuter benefits for transit and parking.
Referral bonus for hired candidates.
Subsidized lunch and parking on in-office days.
100% employer-paid medical, dental, and vision premiums for employees and dependents.
Health Savings Account with annual employer contributions and Flexible Spending Accounts.
Fertility and family-forming benefits.
Expanded mental health support, including therapy and coaching resources.
Hybrid work model with flexibility.
Flexible, take-what-you-need paid time off and company-paid holidays.
Paid medical and parental leave.
Skill development, internal mobility, career pathing, continuous education, and professional development programs.
Financial rewards, peer-to-peer recognition, and growth opportunities.