Sr. Director, Launch Excellence & Operations

Immatics • Houston, TX

3d • $250,000 - $290,000 • Remote

About The Position

The Senior Director, Launch Excellence & Operations serves as a strategic partner and deputy to the Vice President, Launch Excellence, Strategy & Operations, helping shape and execute Immatics' commercial launch strategy. This highly visible role is central to launch planning, governance, and operational readiness, ensuring cross-functional alignment and execution as the organization prepares for commercialization.

The successful candidate will lead integrated launch planning, support the Launch Readiness Review (LRR) process, and establish the operating rhythms, governance, and performance management frameworks needed to drive launch success. The role combines strategy and execution, translating insights into action, guiding critical business decisions, and creating clarity in a dynamic environment.

The role is fully remote in the United States and involves up to 20% travel for cross-functional meetings, treatment center engagement, advisory boards, congresses, and launch activities, including periodic travel to Immatics US in Stafford, Texas. Candidates participate in a structured interview process comprising an initial recruiter video screen, video interviews with the hiring leader and other stakeholders, and a final-stage interview. Applicants must be authorized to work in the United States without current or future sponsorship. Employment is contingent on applicable pre-employment checks.

Requirements

• Bachelor’s degree in life sciences, business, engineering, or a related field and 15+ years of relevant experience, or an MBA or advanced degree (MBA, PhD, MD, or equivalent) and 12+ years of relevant experience.
• A combination of top-tier strategy consulting experience and in-house biopharmaceutical commercial strategy, commercial operations, or launch leadership experience.
• Demonstrated ownership of commercial launch strategy or launch readiness, including launch planning, cross-functional governance, milestone and risk management, and readiness tracking through launch.
• Proven ability to drive strategic decision-making across functions without direct authority by framing decisions, assembling analysis, aligning stakeholders, and driving issues to closure.
• Exceptional executive communication, influencing, and synthesis skills, including the ability to turn complex, ambiguous cross-functional situations into clear recommendations.
• Strong strategic planning and operational execution skills.
• Ability to travel up to 20%, including periodic travel to Stafford, Texas.
• Authorization to work in the United States without current or future sponsorship.

Nice To Haves

• Five or more years of oncology experience; direct experience with TCR, CAR-T, or TIL cell therapies, including a first-wave commercial launch, is strongly preferred.
• Knowledge of personalized manufacturing and vein-to-vein logistics, including manufacturing slot allocation and patient journey management.
• Understanding of the melanoma treatment landscape, therapeutic decision-making, and patient access barriers.
• Working knowledge of the cell therapy operational value chain, including treatment center authorization, apheresis scheduling, chain of identity and chain of custody, and product delivery.
• Experience establishing launch governance, a launch readiness review process, or a commercial PMO from scratch.
• Familiarity with digital launch excellence tools and analytics.
• Experience scoping and managing external consultants, agencies, and analytics vendors.

Responsibilities

• Partner with the VP to develop and execute an integrated launch strategy, roadmap, and commercial playbook.
• Lead strategic evaluations and business cases for critical commercial decisions, capabilities, and growth opportunities.
• Continuously refine launch strategy based on market, competitive, regulatory, and operational insights.
• Develop executive recommendations and materials for senior leadership and key governance forums.
• Drive cross-functional alignment, decision-making, and accountability through the Launch Readiness Review (LRR) process.
• Co-own launch readiness planning, including critical milestones, dependencies, risks, and mitigation strategies.
• Establish and maintain operating rhythms, governance processes, and communication forums that support launch execution.
• Facilitate resolution of complex cross-functional issues and ensure timely escalation of key decisions.
• Build and monitor performance frameworks across the end-to-end cell therapy patient journey.
• Partner with operational teams to identify and address patient funnel attrition, process bottlenecks, and execution risks.
• Provide commercial leadership for systems, analytics, and reporting capabilities that enable launch readiness and operational excellence.
• Develop scalable processes and performance metrics to support successful commercialization.

Benefits

• Competitive rates for health, dental, and vision insurance.
• Four weeks of vacation granted up front each year, prorated for the first and last year of employment.
• 12 company-paid holidays.
• Seven days of sick time.
• 100% employer-paid life insurance up to one times annual salary, capped at $100,000.
• 100% employer-paid short- and long-term disability coverage.
• 401(k) with immediate eligibility and company match: 100% of contributions up to 3% of base salary for the first two years, 4% for years two through three, and up to 5% from the fourth year onward.
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, identity theft protection, and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior