Sr Associate Scientist, Neuroscience, Exploratory Biology
About The Position
Bristol Myers Squibb is seeking a motivated scientist to join its neuroscience exploratory biology group. The role focuses on characterizing disease-relevant biology using primary and iPSC-derived neuronal and glial systems, supporting target validation and mechanism-of-action studies to advance early-stage neuroscience programs. The scientist will design, execute, and troubleshoot experiments involving neurobiological mechanisms and disease-relevant pathways; maintain neuroscience-relevant in vitro systems; perform target-validation and mechanism-of-action studies; and apply molecular, biochemical, imaging, and functional assays. The position also involves rigorous data analysis, documentation, and presentation, collaboration across research teams, and contributing scientific insight to project strategy.
Requirements
- Bachelor's degree in Biology, Neuroscience, Pharmacology, Biochemistry, or a related field, plus 4 or more years of relevant experience; or a Master's degree plus 2 or more years of relevant experience.
Nice To Haves
- Hands-on academic, biotechnology, or pharmaceutical experience, including mammalian cell culture.
- Experience in assay development, target validation, genome editing, genetic perturbation, and mechanism-of-action studies.
- Proficiency in qPCR, JESS, ELISA, immunofluorescence, microscopy, high-content imaging, and analysis.
- Direct experience with primary neuronal cultures, iPSC-derived neurons and glia, and other neuroscience-relevant in vitro systems.
- Ability to independently design, execute, troubleshoot, document, analyze, and present reproducible experiments.
- Data analysis or visualization experience.
- Strong organizational and communication skills, with the ability to work independently and cross-functionally in a fast-paced environment.
- Curiosity, initiative, adaptability, attention to detail, problem-solving, and commitment to scientific rigor, safety, and data quality.
- Strong foundational neuroscience knowledge.
Responsibilities
- Design, execute, and troubleshoot experiments to explore neurobiological mechanisms underlying disease-relevant pathways.
- Culture and maintain primary neuronal cultures, iPSC-derived neurons and glia, and other neuroscience-relevant in vitro systems.
- Perform target-validation studies, including genome editing and genetic perturbation approaches.
- Conduct mechanism-of-action studies to characterize compound or genetic effects on neuronal and glial biology.
- Apply immunofluorescence, microscopy, and high-content imaging and analysis to assess cellular phenotypes.
- Perform qPCR, JESS, ELISA, and MEA to support molecular, biochemical, and functional characterization.
- Analyze, document, and present data with rigor and reproducibility, and contribute to experimental-design discussions.
- Collaborate cross-functionally with computational biology, translational, and drug discovery teams.
- Stay current with neuroscience literature and contribute scientific insight to project strategy.
Benefits
- Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings.
- Flexible Time Off without a set accrual limit for eligible U.S.-based exempt employees, subject to manager approval.
- Eleven paid company holidays each year.
- Eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires, subject to manager approval, and three optional holidays.
- Depending on eligibility, additional time-off benefits may include paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
- Eligible employees receive an annual Global Shutdown between Christmas Day and New Year's Day.
- Potential eligibility for discretionary incentive cash and stock opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
