Associate Scientist II, Biology

Alnylam Pharmaceuticals•Cambridge, MA
•$67,600 - $101,400•Onsite

About The Position

Alnylam is seeking an Associate Scientist II in its Research department to support development of therapeutic programs and the discovery of RNAi compounds for novel indications, with the potential to help advance compounds from the bench to the clinic. The role is part of a multidisciplinary team and involves designing, developing, and executing studies in rodent disease models, evaluating siRNAs in wild-type animals, and performing associated in vitro molecular assays, including transcript and protein quantitation. This is a lab-based, onsite position in Cambridge, Massachusetts.

Requirements

  • Bachelor’s degree in a life sciences-related discipline, such as Molecular Biology, Cell Biology, or Genetics, with 1–3 years of relevant experience, or a master’s degree with 1 year of relevant experience.
  • Proficiency in RNA, DNA, and protein analysis techniques, including RNA isolation, ELISA, western blotting, and RT-qPCR.
  • Experience with cell or tissue culture.
  • Ability to perform and troubleshoot assays independently or with limited direction from supervisors or project leaders.
  • Knowledge of experimental design and underlying scientific principles, and the ability to rigorously and independently analyze results, propose future directions, and generate clear reports.
  • Flexibility and openness to new tasks and challenges, and ability to work on tight deadlines.
  • Proven ability to work in a team environment and across functional areas.

Nice To Haves

  • Basic rodent in vivo skills.
  • Experience setting up rodent disease models.
  • A cover letter is encouraged.

Responsibilities

  • Contribute to the design and execution of studies characterizing compounds for RNAi therapeutic programs, including rodent disease models or other preclinical models.
  • Develop and conduct assays such as qPCR, western blot, and ELISA to support in vivo and in vitro studies.
  • Perform in vitro and cell-based assays to characterize drug activity or mechanism of action.
  • Perform in vivo procedures in rodents, including administration of therapeutics using established methodologies.
  • Analyze and interpret data.
  • Prepare clear experimental reports and data presentations.
  • Prepare and develop protocols and methodologies.
  • Present data to groups within and outside of Research.

Benefits

  • Medical, dental, and vision coverage.
  • Life and disability insurance.
  • Lifestyle reimbursement program.
  • Flexible spending and health savings accounts.
  • 401(k) with a generous company match.
  • Paid time off, wellness days, and holidays.
  • Two company-wide recharge breaks.
  • Family resources and leave.
  • Annual short-term incentive award, such as a bonus or sales incentive.
  • Annual long-term incentive award, such as equity.
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