Sr. Associate Scientist- Formulation Development
About The Position
This position will be part of Drug Product Design and Development (DPDD) within the Pharmaceutical Research and Development (PhRD) department. The incumbent will participate in the development of parenteral formulation for biologics modalities such as monoclonal antibodies, peptide-based therapeutics, antibody drug conjugates, proteins, and vaccines. This position will be responsible for performing analytical characterization of candidate molecules by using various biophysical and biochemical characterization techniques. Furthermore, this position will assist in developing processes for drug product manufacturing, responsible for data compilation, data presentations and report writing. Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines. You will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge. It is your dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.
Requirements
- B.S. in Biochemistry, Chemical/Biochemical Engineering, Pharmacy, Chemistry, Biology, or equivalent with a minimum of 2 years' relevant industry experience.
- Ability to follow established procedures independently is required.
- Working knowledge of SE-UPLC, RP-UPLC, LC-MS, peptide mapping, UPLC (IEX), SDS-PAGE, Capillary Gel electrophoresis (CGE), imaged Capillary Electrophoresis (iCE), spectroscopy techniques.
- Demonstrated scientific documentation skills.
Nice To Haves
- M.S. Degree in above, and 0-2 years of experience preferred.
- Experience with drug development of biologics and vaccines.
- 2-4 years of hands-on lab experience in analytical techniques.
- Excellent documentation skills.
- Self-motivated and highly effective in a team-based environment.
- Effective written and oral communication skills.
- Familiarity with GMP requirements.
- Familiarity with parenteral manufacturing requirements, container/closure integrity, and clinical and commercial unit operations.
- Practical knowledge of lyophilization and lyophilization cycle development.
Responsibilities
- Participate in developing parenteral formulations for biotherapeutic modalities such as monoclonal antibodies, peptide-based therapeutics, antibody drug conjugates, proteins and vaccines.
- Assist in developing manufacturing processes (under general supervision).
- Perform rapid, comprehensive characterization of candidate molecules to determine the stability profile and applying this information to develop an appropriate dosage form to meet clinical needs.
- Assist in the development and scale-up of drug product processes from bench top to pilot scale and, as required, technology transfer to commercial plants.
- Prepare data summary presentation, compile data and author technical reports.
Benefits
- 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
- paid vacation, holiday and personal days
- paid caregiver/parental and medical leave
- health benefits to include medical, prescription drug, dental and vision coverage.
- Relocation assistance may be available based on business needs and/or eligibility.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
High school or GED
