Sr Associate Scientist - Conjugation Chemistry
About The Position
As a Senior Associate Scientist in the Early Bioprocess Development within Pfizer Vaccine Research and Development, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will join a large team of Scientists focused on conjugation process development for manufacturing carbohydrate-based conjugate vaccines. Primary duties include supporting the development and optimization of conjugation methods, purification, and analysis of intermediates and glycoconjugates using chemical and chromatographic methods. The individual will become a key contributor towards supporting the early development and scale up of glycoconjugate vaccines. Careful documentation of work and presentation of data is required. All work is to be done in a compliant manner according to SOP guidelines and cGMP/GLP regulations, where applicable.
Requirements
- BS degree in Chemistry/Biochemistry or related discipline with 3 to 6 years laboratory experience or MS degree in Chemistry/Organic Chemistry or related discipline with 0 to 4 years of experience.
- Strong background in organic chemistry is required.
- Knowledge and ability to operate and maintain relevant instruments, resolve technical problems related to instruments, and execution of analytical methods.
- Independently analyze and provide conclusions regarding experimental data generated.
- Strong verbal and written communication skills are required.
- Experience with documentation of laboratory notebook in an electronic format.
Nice To Haves
- Experience in carbohydrate chemistry
- Hands on experience with various analytical techniques such as HPLC, MALS, UV-Vis, NMR, and other routine lab instruments.
- Proficiency with personal computers including word processing, spreadsheets, PowerPoint, and relevant scientific software
Responsibilities
- Support the development, optimization and scale-up of glycoconjugate vaccine process development.
- In process analysis of glycoconjugates and intermediates.
- Continuously evaluate each process and technique to determine if it is robust, appropriate, and scalable. If an operation has shortcomings or can be improved, propose solution in discussion with other group members to advance objectives.
- Collaborate with colleagues within Vaccine Research and Development organization including Early Bioprocess fermentation, purification, analytical and formulation development groups.
- Participate in the technology transfer of developed process to clinical manufacturing site, both internally and externally, and provide the technical support as needed.
- Fully document laboratory experiments in electronic notebook in a timely and compliant manner and prepare technical reports as needed.
- Perform other duties as assigned.
Benefits
- 401(k) plan with Pfizer Matching Contributions
- Additional Pfizer Retirement Savings Contribution
- Paid vacation, holiday and personal days
- Paid caregiver/parental and medical leave
- Health benefits to include medical, prescription drug, dental and vision coverage
- Relocation support available
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
