Site Management and Monitoring Hub Head (oncology)

AstraZeneca • Wilmington, DE

1d

About The Position

The Oncology Site Management and Monitoring (SMM) Hub Leader provides expert input to global Therapy Area partners and translates the Oncology clinical development strategy into a regional clinical site and market operational plan. Reporting to the Global Head, SMM Oncology, the role oversees operational delivery across the USA and Canada, ensuring interventional trials are delivered on time and to high standards of quality, ethics, and compliance. The role is also accountable for maintaining and developing SMM frameworks that support AstraZeneca’s Oncology and Haematology portfolio.

The position aligns regional objectives with global SMM priorities; establishes effective study leadership and monitoring practices; supports digital strategies and appropriate resourcing; and collaborates with market-level functions and external partners. It leads outsourcing and people strategies, promotes innovation and capability development, and ensures effective clinical-trial processes and systems. The Hub Leader manages budgets and resource forecasts, regional performance metrics, compliance, continuous improvement, and portfolio synergies. The role also hires, manages, develops, and recognises direct reports.

Requirements

• Bachelor’s degree or equivalent qualification in a relevant scientific discipline.
• At least 10 years of relevant experience, with a focus on Development and Patient Safety.
• Relevant pharmaceutical experience in big pharma.
• Leadership experience in a complex environment.
• Ability to communicate effectively with stakeholders across AstraZeneca.
• Mastery of the Clinical Development area, with multidisciplinary experience across functions or within a functional area.

Nice To Haves

• PhD in a scientific discipline.
• Expert reputation within the business and industry, with extensive knowledge of the latest technical and regulatory expectations.
• Ability to engage, influence, and collaborate across boundaries, with a strong problem-solving and delivery focus.
• Ability to assimilate sophisticated information, identify key issues, and communicate clear messages.
• Functional management experience, including resource management, budget planning, and functional planning.

Responsibilities

• Translate the global Oncology strategy into regional clinical site and market operational plans, ensuring operational excellence across the USA and Canada.
• Use competitor intelligence, industry trends, and best-in-class benchmarks to continuously improve regional performance.
• Align regional objectives with global Site Management and Monitoring priorities.
• Identify and implement regional study leadership and monitoring practices that meet Therapy Area needs.
• Optimise digital strategies and ensure appropriate resources are in place for SMM roles at market level.
• Drive collaboration with market-level Medical Affairs, Regulatory, Payor, and institutional partners.
• Lead implementation of outsourcing strategies and build efficient, flexible sourcing models.
• Ensure the function and its people are appropriately trained, equipped, and prepared to deliver.
• Promote excellence across markets, Therapy Areas, and geographies, and identify external trends that support effective deployment of skills, assets, and technologies.
• Maintain and develop frameworks for innovative and effective ways of working with partners.
• Ensure excellence in developing and implementing clinical-trial processes and systems.
• Build, lead, forecast, and update budgets; forecast resource requirements; and implement systems and processes to staff countries efficiently when needed.
• Coordinate financial reporting and ensure adherence to relevant procedures.
• Lead the regional SMM contribution to the global development site operations metrics dashboard and deliver against quality and speed metrics.
• Ensure compliance with ICH/GCP regulations, including applicable CFR requirements.
• Contribute to continuous improvement and share best practices across regions, countries, and departments.
• Identify and lead opportunities for portfolio delivery and synergies across countries in the region.
• Hire, manage, develop, and recognise the performance of direct reports.

Benefits

• Short-term incentive bonus opportunity.
• Eligibility to participate in an equity-based long-term incentive program for salaried roles.
• Qualified retirement program (401(k) plan).
• Paid vacation and holidays.
• Paid leaves.
• Medical, prescription drug, dental, and vision coverage, subject to applicable plan terms and conditions.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior