Senior Technical Program Manager

Precision Neuroscience•Santa Clara, CA

4d•Onsite

About The Position

Precision Neuroscience is building a next-generation brain–computer interface (BCI) to heal and empower millions of people living with neurological conditions. Our first product, Layer 7, is designed to help people with severe paralysis operate digital devices using only their thoughts—opening up new possibilities for daily life. Our team brings together experts in neurosurgery, AI and machine learning, microfabrication, electrical engineering, clinical science, and more. We combine deep technical rigor with a people-first mindset to turn breakthrough research into real-world medical solutions. As a Precision employee, you’ll join one of the fastest-moving and best-capitalized companies in the emerging field of brain–computer interfaces. Since our founding in 2021, we have raised more than $180 million, advanced our technology through validation, and initiated human trials with leading hospitals across the country. Our Values: We build for human impact, measuring progress by the lives our work can change. We do no harm, holding ourselves to the highest standards of safety, integrity, and responsibility. We innovate with urgency because the stakes are high and our users can’t wait. We bring sharp minds, open ears, pairing expertise with curiosity, humility, and respect. And we lead the way, taking ownership of our work and helping to shape the future of our field. We are seeking a Senior Technical Program Manager to lead the end-to-end co-development of a cutting-edge neuronavigation device, driving the program from concept through commercial launch in partnership with a major medical device company. In this role you will have the rare opportunity to build a program from the ground up, guiding technical, regulatory, and strategic work-streams while shaping the processes, partnerships, and team that will define the future of neuronavigation. With the commercial reach and resources of a major industry partner behind you, this is a unique chance to move fast, think big, and leave a lasting mark on the future of neurosurgical care. This position will be based in either our Santa Clara or New York office. We are unable to consider remote workers or individuals who are not currently based in the US and legally authorized to work in the US.

Requirements

Bachelor's degree in Engineering or a related technical field required
6+ years of experience in the Class II or Class III medical device industry, with at least 3–5 years in technical program or project management.
Exceptional written and verbal communication skills, with the ability to translate complex technical and regulatory concepts for non-technical audiences
Proven ability to build and manage complex, cross-functional programs from early development through commercial launch
Proven ability to manage complex, multi-organization relationships, including navigating differing priorities, cultures, and decision-making processes
Ability to make sound decisions under uncertainty and drive alignment when consensus is difficult to achieve, and know when to apply a bias for action
Skilled at building trust and maintaining alignment across senior executives, technical leads, and clinical stakeholders in both organizations
Solid working knowledge of FDA design controls under 21 CFR Part 820 and Quality Management Systems (QMS)
Direct experience with Class II or Class III active implantable medical devices (AIMD) strongly preferred
Experience at both a startup and a large MedTech or medical device company strongly preferred
Familiarity with neurosurgical workflows, OR environments, and the clinical use cases for intraoperative neuronavigation strongly preferred

Responsibilities

Define and own the end-to-end program roadmap from concept through co-branded commercial launch, aligning internal startup milestones with the strategic partner's development and go-to-market timelines
Manage a joint program governance structure, including steering committees, joint working teams, and escalation protocols spanning Precision and the partner organization
Own the day-to-day health of the partnership relationship — proactively identifying and resolving friction points related to scope, timelines, decision rights, or resource allocation
Build and maintain program infrastructure — governance structures, milestone frameworks, and stage gate processes — that satisfy both the startup's agility needs and the partner company's program management standards
With partner counterpart, develop and maintain an integrated master schedule with clear visibility into interdependencies, shared deliverables, and critical path items
Lead resource planning across the startup's lean internal team while coordinating with the partner's dedicated functional resources
Define joint program KPIs and ensure accountability mechanisms work across organizational boundaries
Serve as the authoritative voice on program status for both internal and external audiences, maintaining consistent messaging across organizations
Serve as the primary program integrator across the startup's product, engineering, clinical, regulatory, and quality teams, as well as counterpart functions within the partner organization
Plan and coordinate verification and validation (V&V activities), including clinical validation, across both organizations, ensuring clear ownership of study design, execution, and data rights
Act as the central point of contact and escalation path between the two companies, ensuring consistent communication and aligned priorities at all levels
Partner with the Precision Corporate Development team to protect the company's strategic interests and IP within the collaboration
Lead joint design reviews, stage gate decisions, and co-development working sessions, navigating differing organizational cultures and processes
Identify and manage gaps in team coverage on both sides via fast and effective escalation
Define and execute a joint regulatory strategy in close collaboration with regulatory and quality leads from both organizations, determining ownership of submissions and quality system responsibilities
Ensure program follows Precision Design Controls and QMS foundations in a manner compatible with the partner's quality standards and audit expectations
Maintain DHF ownership and ensure documentation obligations are clearly assigned and fulfilled across both teams
Support 510(k), De Novo, or PMA submission planning, including Pre-Sub meeting preparation and FDA correspondence, coordinating submission ownership with the partner as defined by the collaboration agreement
Own the program-level risk register spanning technical, regulatory, clinical, financial, supply chain, and partnership risks — including risks unique to a co-development model such as misaligned priorities, decision delays, or IP disputes
Lead joint risk reviews with both organizations and develop mitigation plans that account for the complexity of a dual-organization program
Quickly and effectively escalate risks with proposed mitigation strategies, to all relevant stakeholders
Develop deep familiarity with existing system architecture to effectively drive technical decisions across both teams
Manage the interface between the startup's proprietary technology and any platform, infrastructure, or components contributed by the partner, ensuring clean integration and protected IP boundaries
Oversee technical dependencies with contract engineering firms, CROs, and shared or partner-designated suppliers
Drive build-vs-buy and platform decisions in collaboration with both organizations, balancing speed, cost, and strategic control
Own Precision’s program budget, carefully managing internal spend against runway while leveraging partner resources where available under the collaboration agreement
Track and reconcile shared costs, co-investment commitments, and any partner-funded activities as defined in the partnership agreement
Proactively flag budget risks or scope changes that could affect Precision’s financial position