Senior Scientist

STEMCELL Technologies•Vancouver, BC

1d•Onsite

About The Position

STEMCELL Technologies is seeking a Senior Scientist (Manager) to lead an R&D group focusing on the creation of human pluripotent stem cell models using cutting-edge synthetic biology and genome engineering approaches. As a Senior Scientist, you will lead a specialized group of Research Associates to develop methods for stem cell programming and oversee the full lifecycle of product development. You will act as a recognized scientific leader and subject matter expert, driving day-to-day lab functioning and experiments to ensure corporate deliverables are met. By combining your technical expertise and hands-on leadership, you will help shape future product development.

Requirements

PhD with minimum 5 years, Master's with minimum 8 years, or Bachelor's with minimum 10 years of relevant experience in a scientific field (Molecular Biology, Biochemistry, Cell Biology, Stem Cell Biology, or a related discipline)
Extensive knowledge and proven experience using and/or developing genome engineering technologies (such as CRISPR/Cas9), and design strategies including gRNA design parameters, HDR templates, and nucleases to generate engineered cell lines.
Experience with human Pluripotent Stem Cell (hPSC) lines is required
Proven ability to work effectively in cross-functional teams, communicate with key opinion leaders and customers, and provide supervision to junior colleagues
Strong understanding of current genome engineering landscape, including methodologies, applications, and challenges, coupled with the ability to learn and apply scientific knowledge to new fields and contribute to scientific discussions

Nice To Haves

Experience with cellular programming and/or reprogramming approaches such as transcription factor based forward programming is preferred
Practical experience with molecular cloning and/or mRNA synthesis is preferred

Responsibilities

Act as a scientific Subject Matter Expert (SME), leading the technical aspects of complex projects and providing consultancy for intra- and inter-departmental initiatives
Oversee the innovation and optimization of tools to generate diverse cell/tissue types using genome engineering, cell programming, and synthetic biology approaches
Lead and direct the work activities of the group, providing coaching, mentorship, and professional development opportunities to team members
Establish annual goals and oversee multiple high-complexity projects, ensuring rigorous experimental design, research quality, and successful technical support
Consistently apply creative approaches to drive the launch of new products, IP generation, and improved processes, communicating findings effectively with internal and external presentations and collaborating with academic and industrial partners