Senior Scientist - Small Molecule Method Establishment

Thermo Fisher Scientific•Middleton, WI

1d•Onsite

About The Position

The Senior Scientist independently performs complex laboratory testing and provides hands-on technical coaching and mentorship within Thermo Fisher Scientific’s PPD Laboratory Services team. The role is focused on direct laboratory execution, troubleshooting, and improving testing activities while developing subject matter expertise in assigned methods, assays, or analytical platforms. The position may contribute as a non-routine technical specialist in method development, transfer, or validation, or as a key technical resource for complex or priority routine testing. The Senior Scientist owns the quality and technical accuracy of assigned deliverables, such as data, reports, methods, and protocols, within a defined scope. The role does not own overall program delivery, routine study management, project coordination, or primary client relationships. Method-specific technical discussions with clients may occur. Scientific decisions affecting method lifecycle, validation strategy, or broader testing models are escalated to Staff Scientist or higher for approval. This is a fully onsite position at a GMP laboratory in Middleton, Wisconsin. Applicants from anywhere in the United States are welcome, but relocation assistance is not provided. Candidates must be legally authorized to work in the United States without sponsorship and pass a comprehensive background check that includes drug screening.

Requirements

Bachelor’s degree or equivalent and relevant formal academic or vocational qualification.
Comparable to 5+ years of relevant experience, or an equivalent combination of education, training, and experience. In some cases, a suitable combination of education, training, and directly related experience may meet the requirement.
Advanced knowledge of analytical testing techniques, laboratory instrumentation, and method execution in a regulated environment.
Ability to independently execute complex testing, investigations, and non-routine laboratory activities.
Strong troubleshooting, problem-solving, and critical-thinking skills, including identifying analytical challenges and implementing solutions.
Ability to develop and maintain subject matter expertise in assigned methods, assays, or analytical platforms.
Experience with data analysis and identifying trends, outliers, and atypical results.
Strong attention to detail and commitment to data integrity, quality, and accuracy.
Working knowledge of GMP requirements and data integrity principles.
Organizational skills and ability to adapt to changing priorities while maintaining focus, composure, and productivity.
Ability to prioritize and execute multiple assignments with challenging or conflicting deadlines in a dynamic laboratory environment.
Ability to mentor and technically develop scientific staff through hands-on guidance and knowledge transfer.
Strong written and verbal communication skills, especially for technical documentation and scientific discussion.
Ability to collaborate, contribute effectively to a team, and maintain a positive attitude.
Experience identifying and resolving conflicts professionally and constructively.
Ability to maintain confidentiality of client information and data.
Proficiency with Microsoft Office applications, such as Word, Excel, Power BI, PowerPoint, Teams, and SharePoint.
Familiarity with data collection and laboratory software used for analytical testing.
Ability to receive, apply, and act on constructive feedback.
Ability to communicate and understand spoken information and ideas.
Ability to communicate, receive, and understand information and ideas with diverse groups in a comprehensible and reasonable manner.
Ability to work upright and stationary and/or stand for typical working hours.
Ability to lift and move objects up to 25 pounds.
Ability to work in non-traditional work environments and use and learn standard office equipment and technology.
Ability to perform successfully under pressure while prioritizing and handling multiple projects or activities.
Must be legally authorized to work in the United States without sponsorship.
Must pass a comprehensive background check, including drug screening.

Responsibilities

Independently perform complex laboratory testing, including challenging routine testing, analytical investigations, development, transfer, and validation activities.
Communicate analytical needs, resource requirements, and barriers with relevant stakeholders.
Maintain a hands-on laboratory presence and serve as a technical resource during test execution.
Assist directly with testing execution, troubleshooting, and optimization.
Apply scientific judgment to execution strategies, data interpretation, and problem resolution.
Develop and maintain subject matter expertise in analytical methods, assays, or platform technologies.
Serve as an escalation point for execution-level testing issues in routine and non-routine work.
Identify method, execution, and workflow improvements that enhance data quality and routine testing robustness.
Independently execute or technically lead defined components of method development, transfer, or validation work, as appropriate.
Author or review non-routine technical deliverables, including methods, protocols, reports, and quality records.
Support transition of improved or newly established methods into routine testing.
Assist analysts with execution strategies, atypical results, and troubleshooting for established methods.
Support quality management through hands-on data review and root cause analysis.
Train and mentor Scientist I and II staff through direct laboratory involvement and technical coaching.
Reinforce laboratory best practices through example and active participation in testing activities.