Senior Scientist/Team Leader – Bioprocess Development
About The Position
We are seeking a passionate and experienced Senior Scientist/Team Leader – Bioproprocess Development to lead downstream process development team focused on the chromatographic purification of monoclonal antibodies (mAbs). This role is central to our mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently. As a scientific leader, you will guide a team in designing and executing purification strategies that support late-stage development and manufacturing readiness. You’ll work closely with external biopharma clients, helping them advance their molecules toward commercialization—ultimately impacting patient lives around the world.
Requirements
- M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8+ years of relevant industry experience, or Ph.D. with 4+ years of experience in downstream process development for biologics.
- Demonstrated expertise in preparative chromatography and antibody purification.
- Proven ability to lead small scientific teams and manage lab operations.
Nice To Haves
- Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom).
- Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy.
- Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation.
- Experience in client-facing or CDMO environments is a plus.
- Strong communication, organizational, and problem-solving skills.
- Working knowledge of statistical tools (e.g., JMP,) and data analysis software
Responsibilities
- Lead a team of bioprocess development scientists and serve as a subject matter expert in monoclonal antibody downstream processing with a heavy focus on preparative chromatography.
- Partner with leaders across Ecolab’s global Bioprocessing labs to address complex purification challenges.
- Design, execute, and analyze chromatography-based purification processes for mAbs, including Protein A, ion exchange, HIC, and related modalities.
- Develop scalable, robust purification processes tailored to client molecules and manufacturing objectives.
- Lead technology transfer activities with external manufacturing partners.
- Prepare technical reports, protocols, and documentation to support regulatory submissions.
- Work directly with leading biopharma clients to align on study design, timelines, and deliverables.
- Deliver high-quality experimental data that supports client development programs and regulatory filings.
- Act as a trusted scientific partner, helping clients resolve technical challenges and accelerate progress toward commercialization.
- Manage daily lab operations, including equipment maintenance, inventory, and safety compliance.
- Mentor junior scientists and research associates, supporting their technical growth and execution excellence.
- Promote a culture of scientific rigor, operational discipline, and continuous improvement.
Benefits
- Annual bonus pay based on performance
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What This Job Offers
Job Type
Full-time
Career Level
Senior
