Senior Scientist (Small Molecule, Synthetics)

Amgen • Thousand Oaks, CA

9d • $126,066 - $170,560

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Scientist (Small Molecule, Synthetics)

What you will do
Let’s do this. Let’s change the world. In this vital role you will serve as part of the Drug Product Team (DPT), providing creative functional area strategies, crafting and executing DOE’s during the development of pivotal and commercial ready programs. This Amgen leader will apply deep expertise in organic chemistry and their assemblies to develop innovative, fast-paced approaches as part of cross-functional teams. This Amgen’s leader will utilize deep understanding of the organic molecules and their assemblies to develop innovative and fast paced development approaches as part of cross-functional teams. Interface within the DPT department and with other Amgen functions, such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, Biostatistics, etc. The individual will effectively interface within the DPT department and with other Amgen functions, such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, Biostatistics, etc. Design and execute experiments to support drug product development objectives. Summarize results in technical documents, regulatory filings, and presentations. Engage proactively and effectively with external industry groups, such as the IQ Consortium, and academic partners, such as university consortia. Provide technical expertise related to structure, reactivity, and physicochemical properties of materials (drug substance, excipients, etc.)

Requirements

• Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
• OR Master’s degree and 3 years of scientific related experience
• OR Bachelor’s degree and 5 years of scientific related experience

Nice To Haves

• Ph.D. in a relevant scientific field, such as Organic Chemistry, Physical Chemistry, Chemical Engineering, Materials Science, or Pharmaceutical Sciences.
• Strong scientific background for the deep understanding of the organic molecules and their assemblies.
• Profound scientific acumen with a focus on organic chemistry, Physical Chemistry, solid-state chemistry, and the physicochemical properties of small molecules.
• Industry experience: Prior work in the pharmaceutical sector, particularly with oral solid dosage forms.
• Technical proficiency: Familiarity with a wide array of characterization techniques, including but not limited to XRPD, DSC, TGA, and SEM.
• Patent process knowledge: Understanding of the patent application process and the legal framework governing patents is advantageous.
• Demonstrated understanding of scientific principles related to solid dosage forms.
• Manufacturing insights: Comprehensive knowledge of unit operations involved in producing oral solid dosage forms.
• Research leadership: Ability to design, conduct, and complete independent formulation research.
• Publication record: Demonstrated history of research dissemination through publications.
• Team collaboration: Proven track record of effective cross-functional team engagement.
• Writing excellence: Exceptional technical writing capabilities with meticulous attention to detail.
• A proactive, curious, and innovative mindset, with enthusiasm for applying digital solutions to scientific challenges.

Responsibilities

• Serve as part of the Drug Product Team (DPT), providing creative functional area strategies, crafting and executing DOE’s during the development of pivotal and commercial ready programs.
• Apply deep expertise in organic chemistry and their assemblies to develop innovative, fast-paced approaches as part of cross-functional teams.
• Utilize deep understanding of the organic molecules and their assemblies to develop innovative and fast paced development approaches as part of cross-functional teams.
• Interface within the DPT department and with other Amgen functions, such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, Biostatistics, etc.
• Effectively interface within the DPT department and with other Amgen functions, such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, Biostatistics, etc.
• Design and execute experiments to support drug product development objectives.
• Summarize results in technical documents, regulatory filings, and presentations.
• Engage proactively and effectively with external industry groups, such as the IQ Consortium, and academic partners, such as university consortia.
• Provide technical expertise related to structure, reactivity, and physicochemical properties of materials (drug substance, excipients, etc.)

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree