Senior Scientist I, Clinical Biomarker Development

Revolution MedicinesRedwood City, CA
Onsite

About The Position

The Senior Scientist I in Clinical Biomarker Development team, within Translational Medicine will play a key role in the design, execution, and interpretation of clinical biomarker strategies across Revolution Medicine’s oncology pipeline. You will: Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms. Support biomarker implementation for early- and late-stage oncology clinical trials. Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs. Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams. Contribute to clinical protocols, study reports, and regulatory documents (e.g., INDs, IBs, CSRs). Translate preclinical findings into clinically actionable biomarker hypotheses. Stay current with emerging biomarker technologies and trends in precision oncology.

Requirements

  • PhD in a relevant scientific discipline with 3+ years of relevant industry experience in clinical biomarkers, translational medicine, or related roles.
  • Experience supporting oncology clinical trials with biomarker components.
  • Familiarity with biomarker platforms such as genomic, transcriptomic and proteomic assays.
  • Experience working with CROs and managing external vendors.
  • Strong scientific communication skills and ability to work cross-functionally.

Nice To Haves

  • Experience with targeted oncology therapies or RAS/MAPK pathway biology.
  • Biological understanding of pancreatic, non-small cell lung and/or colorectal cancers is preferred.
  • Familiarity with analytical software and analytical capabilities for integrating clinical and biomarker datasets.

Responsibilities

  • Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms.
  • Support biomarker implementation for early- and late-stage oncology clinical trials.
  • Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs.
  • Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams.
  • Contribute to clinical protocols, study reports, and regulatory documents (e.g., INDs, IBs, CSRs).
  • Translate preclinical findings into clinically actionable biomarker hypotheses.
  • Stay current with emerging biomarker technologies and trends in precision oncology.

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Education Level

Ph.D. or professional degree

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