Sr. Scientist, Biomarker Discovery
About The Position
As a Sr. Scientist in Biomarker Discovery, you will play a pivotal role in advancing immunology therapeutics within our organization. Working with the WCH team, you will lead and execute cutting-edge biomarker research across non-clinical and clinical stages. Your expertise will be crucial in generating high-quality biomarker data from non-human primate and human samples, focusing on mechanism of action, target engagement, and immune pathway modulation. This position requires a strong hands-on approach to experimental work, particularly in flow cytometry-based assays, while collaborating closely with clinical and translational partners. Your contributions will be essential in bridging immune biology with clinical development, providing decision-enabling insights that drive clinical strategies and therapeutic advancements.
Requirements
- PhD in Immunology or related biomedical science field (Bachelors or Masters with additional directly relevant experience may be considered).
- 2+ years of relevant industry or translational research experience supporting clinical-stage immunology programs (6+ years with MS, 8+ years with BS).
- Expertise in flow cytometry based assays and biomarker development.
- Strong analytical and experimental skills in immunology research.
- Excellent communication skills to convey scientific insights effectively.
Nice To Haves
- Experience in assay qualification and method transfer to CROs.
- Proficiency in immune phenotyping, receptor occupancy, and pharmacodynamic readouts.
- Familiarity with clinical biomarker data review and interpretation.
Responsibilities
- Lead and execute clinical and translational biomarker research to establish mechanism of action, target engagement, and immune pathway modulation for clinical-stage immunology therapeutics.
- Independently design, perform, analyze, and interpret experiments using primary human samples to generate robust, decision-enabling biomarker data.
- Develop, optimize, and own multiparameter flow cytometry–based clinical biomarker assays, including immune phenotyping, receptor occupancy, and pharmacodynamic readouts.
- Support assay qualification, method transfer to CROs, and longitudinal clinical biomarker data review, ensuring assay robustness and interpretability.
- Communicate biomarker insights clearly to cross-functional stakeholders to influence clinical strategy, study interpretation, development decision, and scientific narrative.
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
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What This Job Offers
Job Type
Full-time
Career Level
Manager
Education Level
Ph.D. or professional degree
