Senior Scientist I - Analytical Development

AbbVieWorcester, MA
Onsite

About The Position

AbbVie is searching for a highly motivated Scientist I to join our Analytical Development team at AbbVie Bioresearch Center in Worcester, MA. Our team is responsible for the development, qualification, and execution of analytical methods to provide product and process understanding for biological entities from discovery through commercial stages. The successful candidate will be a part of the Biomolecular Interaction Group within the Analytical Development Department. The Biomolecular Interactions Group is mainly focused on method development and implementation of various immunoassays to monitor process impurities and to assess potency of AbbVie’s Biologics to support product and process development for early-phase, late-phase, and commercial programs. Some of the techniques/methods utilized in the group include 1) ELISAs to monitor and detect process related impurities; 2) surface plasmon resonance using Biacore for assessment of antigen binding and binding of antibody Fc receptors and 3) qPCR to measure levels of residual DNA and mycoplasma.

Requirements

  • BS or equivalent education in Biology, Biochemistry, Engineering or related discipline and 10+ years of experience in the biopharmaceutical industry; MS and 8+ years experience; PhD and 0+ years experience.
  • Industry experience in method development, qualification, validation, and method transfer
  • Proficiency with Windows 10 and Microsoft Office (Outlook, Teams, Excel, Word, and PowerPoint)
  • Excellent written communication, oral communication, organization, and multitasking skills
  • Hardworking and motivated to drive both efficiency and quality
  • Understand and adhere to corporate standards regarding code of conduct, safety, and appropriate handling of materials

Nice To Haves

  • Theoretical and practical knowledge of ELISA technology to effectively interpret and troubleshoot is desirable

Responsibilities

  • Sample preparation involving excellent pipetting skills
  • Performance of enzyme-linked immunosorbent assays (ELISAs) to monitor impurities and to assess antigen binding
  • Performance of basic data acquisition and statistical analysis with clear and concise documentation in electronic lab notebooks
  • Reporting results to stakeholders in a clear and concise manner
  • Assist with method development and lab equipment maintenance

Benefits

  • paid time off (vacation, holidays, sick)
  • medical/dental/vision insurance
  • 401(k)
  • short-term incentive programs
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