Senior Scientist I, Analytical Chemistry

AbbVie•North Chicago, IL

1d•$96,500 - $183,500•Onsite

About The Position

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. This role will lead the analytical aspects of a project, including method development and validation, control strategy development, specification justification, data generation, and regulatory submission contributions. The scientist will leverage experience in analytical techniques relevant to peptide product development, understand and apply advanced analytical techniques to generate extended characterization data packages, and build deep knowledge of API processes to implement analytical controls and testing. The position involves formulating conclusions, designing follow-on experiments, and potentially initiating new areas of investigation. Data processing, interpretation, and visualization are key, as is communication and collaboration with cross-functional groups. The role requires scientific initiative, creativity, and a high level of productivity in the lab, while adhering to corporate standards for code of conduct, safety, material handling, and GxP compliance.

Requirements

Ph.D. in Analytical Chemistry with 0 to 4 years of peptide-related industry experience.
Strong chromatography knowledge and proven ability to develop, troubleshoot, and improve methods across common techniques such as UHPLC, GC, IC, etc.
Highly autonomous and productive in performing laboratory research or method development independently, requiring only minimal direction from a supervisor.
Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
Familiarity with forced degradation, impurity tracking, and stability requirements for peptide products.
Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Nice To Haves

Understanding of cGMP and regulatory requirements.
Practical knowledge of modern peptide manufacturing processes, organic structure, functional groups, chemistry.
Familiarity with chemical biology fundamentals and related analytical techniques including recombinant protein expression and purification, cell culture, immunoassays, and gels.

Responsibilities

Lead the analytical aspects of a project including method development and validation, control strategy development, specification justification, data generation, and regulatory submission contributions.
Leverage experience in analytical techniques relevant to peptide product development including mass spectrometry, chromatography, amino acid analysis, advanced separation techniques, and higher-order structure studies.
Understand and apply advanced analytical techniques to generate extended characterization data packages to build product knowledge and support regulatory requirements.
Build deep knowledge of API processes spanning starting materials, intermediates, impurities, and the API to implement analytical controls and testing to enhance process and product knowledge.
Formulate conclusions and design follow-on experiments based on multidisciplinary data.
May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
Process, interpret, and visualize data to facilitate project team decisions.
Communicate and collaborate with cross-functional groups and departments.
Routinely demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab.
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, and GxP compliance, where applicable.