Mass-Spec Analytical Chemistry Scientist

Certified Group•Kitchener, ON

5d•CA$85,000 - CA$110,000

About The Position

The Scientist will serve as a technical leader and subject matter expert responsible for high-complexity analytical testing in support of an FDA proposal. The role requires extensive hands-on experience operating, maintaining, and troubleshooting advanced chromatography and mass spectrometry instrumentation, including GC-MS platform.

Requirements

PhD/MSc, Chemistry; 5+ years of experience
GC-MS technology specializing in NTA (Non-targeted Analysis) for the identification of unknowns
Advanced technical understanding of GC-MS and/or LC-qTOF theory, operation, maintenance, and troubleshooting.
Strong understanding of advanced chromatography techniques, including GC-MS and/or LC-qTOF.
Experience with Agilent systems.
Experience in advanced chromatography techniques, method development, routine testing, problem solving, and unknown determination.
Ability to read and interpret chromatograms, mass spectra, analytical reports, and method performance data.
Manual dexterity required for instrument maintenance and sample preparation.
Excellent communication skills in English, both oral and written, for technical documentation, reporting of experimental results, and oral presentations.
Ability to present technical concepts and simulated or experimental results clearly to technical and non-technical audiences.
Well organized and able to work independently to complete projects, while also contributing effectively as part of a team.
Demonstrated ability to support high-complexity analytical testing through sound judgment, attention to detail, and proactive problem solving.

Nice To Haves

Estimated 498 NTA analysis
228 Forced Degradation replicates over 2 months (38 Sample Types X 3 Replicates X 2 Conditions/Timepoint variants)
270 Stability Study replicates (over 12 months)

Responsibilities

Preparation of test samples for analysis including forced degradation and stability testing
Independently operate, maintain, and troubleshoot analytical systems.
Perform routine and advanced instrument maintenance, including column replacement, and performance verification.
Diagnose complex instrument and method performance issues and implement corrective actions to minimize downtime.
Serve as a technical resource for instrument performance, repairs, vendor interactions, and troubleshooting support.
Maintain accurate and complete technical records.
Evaluate and trend QA/QC metrics, including internal standards, surrogates, blanks, laboratory control samples, matrix spikes/matrix spike duplicates, and calibration criteria (where applicable).
Assist in developing technical documentation, validation summaries, method performance studies, and related reports.