Biomarker

Thermo Fisher Scientific•Boston, MA

8d•Onsite

About The Position

At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future. Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

Requirements

Prior hands-on experience developing ligand binding assays for translational or clinical applications.
Experience developing and validating assays, with working knowledge of assay validation expectations and fit-for-purpose principles.
Method development and validation experience (Ligand binding assays, Immunoassays, ELISA)
Biomarker Assay optimization and troubleshooting
Western blot
Protein labeling and quantification
Molecular biology techniques
Cell biology techniques
Data interpretation and presentation
Must be legally authorized to work in the United States without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.

Responsibilities

Design and execute method development activities for innovative biomarker assays intended for use as primary, secondary, or exploratory endpoints in clinical trials.
Evaluate assay feasibility and strategies for the measurement of novel biomarkers in relevant biological matrices, including human biofluids and tissues.
Collaborate with senior members of the Biomarkers group and cross-functional partners to develop, optimize, and implement high-quality biomarker assays.
Apply knowledge of biomarkers, translational medicine, and assay validation principles to design robust assays suitable for clinical trial use and aligned with regulatory expectations, including FDA requirements.
Perform mock validation experiments and contribute to generation of data packages supporting assay readiness.
Support assay transfer activities to CROs and external laboratories, including technical handoff and troubleshooting as needed.
Analyze, interpret, and clearly communicate experimental results to internal stakeholders and project teams.
Present data at team and project meetings as needed.

Benefits

Competitive remuneration
Annual incentive plan bonus
Healthcare
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO)
10 paid holidays annually
Paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave)
Accident and life insurance
Short- and long-term disability
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount