Senior Scientist – ELISA / LBA / Biomarker

Thermo Fisher Scientific • Boston, MA

10d • $95,000 - $105,000 • Onsite

About The Position

Thermo Fisher Scientific's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner. Our Laboratories Functional Service Partnership (FSP) team plays a direct role in advancing drug development by creating sustained groups of talent within our customers’ organizations to provide long-term support. Through this collaborative approach, our professionals bring their commitment to excellence, industry knowledge, and operational strength directly into customer environments, helping to enhance capabilities and advance the delivery of life-changing therapies.

Requirements

• Method development and validation experience (Ligand binding assays, Immunoassays, ELISA)
• Biomarker Assay optimization and troubleshooting
• Western blot
• Protein labeling and quantification
• Molecular biology techniques
• Cell biology techniques
• Data interpretation and presentation
• Bachelor's degree in lab sciences such as Chemistry, Biochemistry, Material Science, Immunology, Biology, Molecular Biology or similar
• Sr. Scientist: Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4+ years’)
• OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 2+ years’)
• OR PhD
• In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary and/or standing for typical working hours.
• Able to lift and move objects up to 25 pounds
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technology with proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Responsibilities

• Prior hands-on experience developing ligand binding assays for translational or clinical applications.
• Experience developing and validating assays, with working knowledge of assay validation expectations and fit-for-purpose principles.
• Design and execute method development activities for innovative biomarker assays intended for use as primary, secondary, or exploratory endpoints in clinical trials.
• Evaluate assay feasibility and strategies for the measurement of novel biomarkers in relevant biological matrices, including human biofluids and tissues.
• Collaborate with senior members of the Biomarkers group and cross-functional partners to develop, optimize, and implement high-quality biomarker assays.
• Apply knowledge of biomarkers, translational medicine, and assay validation principles to design robust assays suitable for clinical trial use and aligned with regulatory expectations, including FDA requirements.
• Perform mock validation experiments and contribute to generation of data packages supporting assay readiness.
• Support assay transfer activities to CROs and external laboratories, including technical handoff and troubleshooting as needed.
• Analyze, interpret, and clearly communicate experimental results to internal stakeholders and project teams.
• Present data at team and project meetings as needed

Benefits

• competitive remuneration
• annual incentive plan bonus
• healthcare
• A choice of national medical and dental plans, and a national vision plan, including health incentive programs
• Employee assistance and family support programs, including commuter benefits and tuition reimbursement
• At least 120 hours paid time off (PTO)
• 10 paid holidays annually
• paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave)
• accident and life insurance
• short- and long-term disability
• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

What This Job Offers

• Job Type: Full-time
• Career Level: Senior