Senior Scientist, Discovery Process Research

Johnson & Johnson • Spring House, PA

6d • Onsite

About The Position

Our Discovery Process Research team focuses on developing novel synthetic chemistry solutions that enable and accelerate the Discovery of innovative therapeutics to treat diseases with high unmet medical need. You will be responsible for conducting research towards identifying creative solutions for chemistry problems across a portfolio of projects in the discovery space, from lead identification through selection of development candidates. Our goal is to facilitate medicinal chemistry research by finding solutions to synthetic bottlenecks, enabling access to novel chemical space and translating chemistry innovations to the development of efficient routes for the synthesis of small molecules, oligonucleotides, peptides and other emerging modalities advancing into development. Your work will require state of the art synthetic organic chemistry skills and understanding of analytical chemistry techniques. You are expected to remain conversant with the modern chemical literature and to maintain a strong laboratory presence. Residing at the interface of Discovery and Development, Discovery Process chemists thrive by collaborating across multiple Pharmaceutical R&D disciplines. Unique to this role, Senior Scientists in Discovery Process are expected to operate with a high degree of independence for scientific decision-making to contribute to the direction and execution of Discovery programs from very early in their careers.

Requirements

• Minimum of a PhD in Synthetic, Organic, Medicinal Chemistry, or related field completed by Spring of 2027 is required
• Experience in methodology development, catalysis, total synthesis or similar
• Proven track record of scientific excellence supported by peer-reviewed publications
• Ability to collaborate in a highly integrated environment and to work in a strong team with diverse backgrounds.
• Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives.
• Highly motivated candidate with strong commitment to lab work.
• Excellent oral and written communication skills, fluent in English both verbal and in writing.

Nice To Haves

• Hands on knowledge of high throughput experimentation set-ups
• Experience working in non-small molecule modalities such as peptides (solid or solution phase synthesis), bioconjugates such as ADCs, or proximity inducers

Responsibilities

• Conducting research towards identifying creative solutions for chemistry problems across a portfolio of projects in the discovery space, from lead identification through selection of development candidates.
• Facilitate medicinal chemistry research by finding solutions to synthetic bottlenecks, enabling access to novel chemical space and translating chemistry innovations to the development of efficient routes for the synthesis of small molecules, oligonucleotides, peptides and other emerging modalities advancing into development.
• Maintain a strong laboratory presence.
• Collaborate across multiple Pharmaceutical R&D disciplines.
• Operate with a high degree of independence for scientific decision-making to contribute to the direction and execution of Discovery programs.

Benefits

• Inclusive work environment where each person is considered as an individual.
• Respect for the diversity and dignity of employees and recognition of their merit.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree