Senior Scientist, Cell Therapy TRC In Vivo Pharmacology

Bristol Myers Squibb • Seattle, WA

12d • Onsite

About The Position

The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes.” Position Summary The In Vivo Pharmacology team in the Cell Therapy Thematic Research Center has an opening for a highly collaborative and creative Sr. Scientist with a dedication to discovery and development of novel engineered immune effector cell therapeutics for the treatment of cancer and other chronic diseases. The successful candidate will have a strong scientific track-record demonstrating their expertise in immuno-oncology, particularly related to tumor and immune response models in mice, and a desire to lead functional workstreams from early stages/target concept through to IND filing. The role will encompass the direct supervision and mentorship of research associates and contribute to scientific and strategic leadership for the pharmacology function in the context of collaborative, cross-functional BMS R&D project teams. This position is ideal for a motivated and interactive scientist who is passionate about cell therapy and has a proven track record working across highly matrixed teams to drive key decisions for drug discovery and development.

Requirements

• Bachelor’s Degree and 7+ years of academic and / or industry experience
• Master’s Degree and 5+ years of academic and / or industry experience
• Ph.D. or equivalent advanced degree in the Life Sciences
• 2+ years of academic and / or industry experience

Nice To Haves

• Ph.D. in Immunology, Cancer Biology, Virology or a related field with demonstrated expertise in in vivo immuno‑oncology models and immune effector cell biology
• 4+ years of post‑degree experience in industry settings focused on immune‑based therapies, in vivo immunology, or engineered cell therapies
• Advanced proficiency in murine tumor model development—including syngeneic, xenograft, and/or T‑cell driven models—with a track record of designing and executing studies that inform mechanistic understanding and therapeutic advancement including: cell-based therapies, immunotherapies, and drug combination studies
• Familiarity with gene editing technologies and delivery methods (e.g., adeno-associated viral vectors, non-viral delivery, CRISPR gene editing)
• Proven capability to influence project direction through clear communication, scientific leadership, and representation of the in vivo pharmacology function in cross‑functional settings.
• Strong record of scientific authorship, including internal reports, external publications, and contributions to patents or regulatory documentation.

Responsibilities

• Lead functional workstreams on highly matrixed cell therapy research project teams from target concept to IND
• Represent the in vivo pharmacology function on cross‑functional research teams, effectively influencing scientific decisions, building alignment, and communicating clear scientific recommendations.
• Independently design, execute, and interpret complex in vivo pharmacology studies supporting engineered immune cell therapy programs, ensuring next logical steps based on experimental results.
• Independently author high‑quality scientific documents, including presentations, study reports, protocols, and publications; contribute to regulatory and IP filings.
• Present complex concepts to a range of audiences including governance and departmental meetings
• Integrate literature, emerging technologies, and evolving immunotherapy modalities to enhance study design and support the development of novel engineered immune cell therapeutics.
• Supervise and mentor colleagues through functional guidance, scientific feedback, and day‑to‑day technical support, fostering strong technical execution and scientific rigor.
• Excel in a fast-paced team environment, meet deadlines, and prioritize work on multiple projects while fostering open and productive scientific communication and collaboration

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
• The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree