Associate Scientist, In Vivo Pharmacology, Cell Therapy

Bristol Myers Squibb • Seattle, WA

7d • Onsite

About The Position

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. Position Summary The individual hired for this role will contribute to the development and implementation of a broad range of tumor models to support the preclinical development of novel immunotherapies. The role will provide opportunities for the candidate to actively participate in the team’s study planning and in scientific discussions related to in vivo pharmacology projects. There will also be opportunities to train in more advanced in vivo procedures and immunological assays.

Requirements

• Bachelor's Degree
• 2+ years of academic / industry experience

Nice To Haves

• 4+ years of experience in animal care and husbandry, including proficiency in monitoring and caring for mouse models of disease (e.g., cancer or autoimmune models).
• Experience handling both immune-competent and immune-deficient murine tumor models is highly preferred.
• The successful candidate will be experienced with mouse dosing techniques, including oral gavage, intraperitoneal injection, and subcutaneous injection.
• Experience with mouse blood collection techniques (e.g., saphenous, jugular, retro-orbital, and submental)
• Experience with mouse tissue collection and processing for ex vivo assays
• Experience with flow cytometry and immunoassays (e.g., Luminex, MSD, ELISA)
• Experience with small-molecule drug formulation
• Experience with in vivo imaging systems (IVIS)
• Excellent record-keeping skills, including experience with data entry and data management; proficiency with Benchling and StudyLog software are highly preferred
• Proficiency with Microsoft Excel, Word, and PowerPoint
• Experience with FlowJo and analysis tools like GraphPad Prism
• Ability to work both independently and collaboratively in a fast-paced team environment

Responsibilities

• Support in vivo efficacy and PK studies for preclinical evaluation of cell therapies in mouse tumor models.
• Perform core in vivo procedures, including tumor inoculation, animal health checks, tumor and bodyweight measurements, drug dosing, sample collection, and data entry.
• Assist with moderate amount of mammalian cell culture using sterile technique
• Apply scientific and technical skills to execute assigned work, analyze experimental data, and communicate results within the work group
• Execute simple experimental plans with appropriate controls and contribute to experiment design within the work group
• Work with minimal supervision on routine activities and with moderate supervision on non-routine activities

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
• Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level