Senior Scientist - Bioanalytical & Biomarker Technologies

Regeneron Pharmaceuticals • Tarrytown, GA

1d • Onsite

About The Position

We are seeking a highly motivated bioanalytical scientist who can contribute to the development and implementation of state-of-the-art quantitative and qualitative analytical and bioanalytical methods to support biopharmaceuticals in discovery and preclinical development pipeline at Regeneron. The successful candidate need function well in a collaborative, fast-paced, multidisciplinary team environment.

Requirements

• Chemistry, Biochemistry, Pharmaceutical Science or a related discipline, B.S. with 10+ yrs, MS with 8+ yrs, or Ph.D. with 0-6 yrs postdoctoral experience.
• Proven expertise and extensive experience in liquid chromatography and mass spectrometry is required, with demonstrated track record of successfully developing MS, LC-MS or LC-MS/MS method.
• Hands on experience in sample preparation technique (LLE, SPE, Immunocapture, enzymatic digestion, homogenization etc.) and automation platform.
• Scientific curiosity and strong capabilities in experimental design, execution, data interpretation and troubleshooting with limited supervision.
• Ability to think critically and to prioritize and manage multiple projects under aggressive timeline in a fast-paced environment.
• Detail-oriented, good interpersonal and effective technical writing and verbal communication skills.

Nice To Haves

• Industrial experience in bioanalysis of LC-MS based small molecule, siRNA, biomarkers and biotherapeutics assay development is preferred.
• Previous experience in GLP lab and mass spectrometry applications in ADC analytics, metabolomics and proteomics would be advantageous.

Responsibilities

• Primarily responsible for developing LC‑MS–based bioanalytical methods in various biological matrices.
• Apply these methods to quantify biotherapeutic levels, assess in vitro stability, evaluate in vivo biotransformation, and measure biomarkers (small molecules, peptides, and proteins).
• Support characterization of drug candidates and critical reagents within the discovery pipeline.
• Collaborate closely with chemistry, conjugation, biology, PK, and TK teams to ensure strong experimental design, accurate data interpretation, and informed decision‑making.
• Contribute to advancing programs involving bioconjugates, oligonucleotides, bispecifics, and other therapeutic modalities.
• Explore and evaluate innovative bioanalytical technologies and emerging platforms to support an evolving portfolio, including novel molecular modalities and therapeutic areas.
• Document experiments, results, and findings in an electronic lab notebook.
• Present scientific work at internal and external meetings.
• Perform general lab and instrument maintenance.
• Grow into the role of bioanalytical representative on cross‑functional project teams, effectively managing priorities to meet multiple project goals and timelines.

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree